Mutagenicity Data of Water Extracts
The dataset contain the primary mutagenicity data. It consists of the number of mutant colonies (called revertants) per petri plate at each dose of the water extract as used in the Salmonella (Ames) bacterial mutagenicity assay. The dataset also shows graphically the dose-response curves constructed from the primary data, as well as a table showing the slopes of those curves, which are the mutagenic potencies of the water expressed as revertants/ml-equivalents.
This dataset is associated with the following publication:
Berninger, J., D. Demarini, S. Warren, J. Simmons, V. Wilson, J. Conley, M. Armstrong, D. Kolpin, K. Kuivila, T. Reilly, K. Romanok, D. Villeneuve, and P. Bradley. Predictive Analysis Using Chemical-Gene Interaction Networks Consistent with Observed Endocrine Activity and Mutagenicity of U.S. Streams. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 53(15): 8611-8620, (2019).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "David Demarini",
"hasEmail": "mailto:demarini.david@epa.gov"
}
|
| description | The dataset contain the primary mutagenicity data. It consists of the number of mutant colonies (called revertants) per petri plate at each dose of the water extract as used in the Salmonella (Ames) bacterial mutagenicity assay. The dataset also shows graphically the dose-response curves constructed from the primary data, as well as a table showing the slopes of those curves, which are the mutagenic potencies of the water expressed as revertants/ml-equivalents. This dataset is associated with the following publication: Berninger, J., D. Demarini, S. Warren, J. Simmons, V. Wilson, J. Conley, M. Armstrong, D. Kolpin, K. Kuivila, T. Reilly, K. Romanok, D. Villeneuve, and P. Bradley. Predictive Analysis Using Chemical-Gene Interaction Networks Consistent with Observed Endocrine Activity and Mutagenicity of U.S. Streams. ENVIRONMENTAL SCIENCE & TECHNOLOGY. American Chemical Society, Washington, DC, USA, 53(15): 8611-8620, (2019). |
| distribution |
[
{
"title": "USGS Mutagenicity Data 7-2-18 .pdf",
"mediaType": "application/pdf",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1504446/USGS%20Mutagenicity%20Data%207-2-18%20.pdf"
}
]
|
| identifier | https://doi.org/10.23719/1504446 |
| keyword |
[
"Ames assay",
"Mutagenicity",
"U.S. streams",
"chemical-gene networks"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2019-09-17 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1021/acs.est.9b02990"
]
|
| rights |
null
|
| title | Mutagenicity Data of Water Extracts |
