Patent AT-E399538-T1: [Translated] MATRIX PREPARATIONS FOR THE CONTROLLED PRESENTATION OF MEDICINAL MEDICINAL PRODUCTS

A controlled release pharmaceutical composition for oral use in the form of a coated matrix composition, the matrix composition comprising ni) a mixture of a first and a second polymer that have plasticizing properties and which have melting points or melting intervals of a temperature of at the most 200 °C, nthe first polymer being selected from the group consisting of polyethylene glycols and polyethylene oxides having a molecular weight of at least about 20,000 daltons in crystalline and/or amorphous form or a mixture of such polymers, and nthe second polymer being selected from block copolymer of ethylene oxide and propylene oxide including poly(ethylene-glycol-b-(DL-lactic acid-co-glycolic acid) - b- ethylene glycol (PEG-PLGA PEG), poly((DL-lactic acid-co-glycolic acid) - g-ethylene glycol) (PLGA-g-PEG), poloxamers and polyethylene oxide - polypropylene oxide (PEO-PPO), nii) a therapeutically, prophylactically and/or diagnostically active substance, nwherein the concentration of the second polymer in the matrix composition is from 5 to 90% w/w, nthe matrix composition being provided with a coating, which is substantially insoluble in and impermeable to fluids such as body fluids during the intended release periods, the coating having at least one opening exposing at one surface of said matrix, the coating comprising one or more polymers, which are possible to process by extrusion, solution, or in the form of a dispersion, the one or more polymers being selected from the group consisting of: ncellulose acetate, polyamide, polyethylene, polyethylene terephthalate, polypropylenem polyurethane, polyvinyl acetate, polyvinyl chloride, silicone rubber, latex, polyhydroxybutyrate, polyhydroxyvalerate, teflon, polylactic acid or polyglycolic acid and copolymers thereof, copolymers such as ethylene vinyl acetate (EVA), styrene-butadienestyrene (SBS) and styrene-isoprene-styrene (SIS).

                                            [
  "009:25"
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                                            {
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    "description": "Access the complete Patent AT-E399538-T1: [Translated] MATRIX PREPARATIONS FOR THE CONTROLLED PRESENTATION OF MEDICINAL MEDICINAL PRODUCTS on the official website.",
    "downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E399538-T1"
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                                            [
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                                            {
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