Patent AT-E400301-T1: [Translated] ARTERIOVENOUS AND VENOUS TRANSPLANT TREATMENTS: METHODS AND COMPOSITIONS
A method and compounds are provided for inhibiting the synthesis of extracellular matrix proteins. Compounds of the invention comprise oligonucleotides specific for nuclear proto-oncogenes. Preferably, oligonucleotides of the invention are selected from the group consisting of c-myc and c-myb and are locally administered. The invention finds use in the treatment of a variety of disorders, including sclerotic disorders and restenosis, associated with the inappropriate synthesis of extracellular matrix proteins, particularly collagen.
Complete Metadata
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| accessLevel | public |
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"fn": "NIH/NCBI Data Team",
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| description | A method and compounds are provided for inhibiting the synthesis of extracellular matrix proteins. Compounds of the invention comprise oligonucleotides specific for nuclear proto-oncogenes. Preferably, oligonucleotides of the invention are selected from the group consisting of c-myc and c-myb and are locally administered. The invention finds use in the treatment of a variety of disorders, including sclerotic disorders and restenosis, associated with the inappropriate synthesis of extracellular matrix proteins, particularly collagen. |
| distribution |
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|
| identifier | https://healthdata.gov/api/views/mtsh-r6k4 |
| issued | 2025-09-05 |
| keyword |
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| landingPage | https://healthdata.gov/d/mtsh-r6k4 |
| modified | 2025-09-06 |
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| publisher |
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| theme |
[
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|
| title | Patent AT-E400301-T1: [Translated] ARTERIOVENOUS AND VENOUS TRANSPLANT TREATMENTS: METHODS AND COMPOSITIONS |