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Patent AT-E400303-T1: [Translated] COMBINED IMAGING CONTRAST AGENTS AND SYSTEMS AND METHODS THEREOF

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Metadata Last Checked: September 07, 2025 | Last Modified: 2025-09-06
In accordance with embodiments of the present technique, a combined modality imaging system (10) includes a first imaging device of a first modality (12) and a second imaging device of a second modality (14) that is different from the first modality (12). The first and the second imaging devices are both adapted to interact with a contrast agent (18) adapted to be received in a subject (16). The contrast agent (18) includes a deformable particle that has a geometry that varies in response to an emission from the first imaging device. The deformable particle also includes a fluorescent component (70) adapted to emit electromagnetic radiation (28) that is detectable by the second imaging device and a quenching component (72) separated from the fluorescent component (70) at a distance based on the geometry and that which is adapted to absorb a portion of the electromagnetic radiation (28) from the fluorescent component (70).

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