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Patent AT-E400568-T1: [Translated] SUBSTITUTED 4-(4-PIPERIDINE-YL-PIPERAZINE-1-YL)-AZEPAN DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Metadata Last Checked: September 07, 2025 | Last Modified: 2025-09-06
The invention concerns substituted 4-(4-piperidin-4-yl-piperazin-1-yl)-azepane derivatives having neurokinin antagonistic activity, in particular NK~antagonistic activity, their preparation, compositions comprising them and their use as a medicine, in particular for the treatment of pain, emesis, anxiety, depression and IBS.

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