Patent AT-E40103-T1: [Translated] CYCLOHEXENEMETHANOL DERIVATIVE WITH MUCOSECRETOLYTIC ACTIVITY, ITS MANUFACTURING PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT.
A novel derivative of (-)-6,6-dimethylbicyclo [3.1.1] ept-2- ene-2-ethanol (J.P. Bain. J. Am. Chem. Soc. 1946, Vol. 68, page 638) is disclosed. The patent composition is marketed e.g. under the name nopol, v. The Aldrich-Europe Catalog Handbook of Fine Chemicals, item 3160-5 nopol 98% 128-50-7.The object of the present invention is the compound of formula (I) : 4-(2-hydroxyethyl) -a a dimethyl-5-hydroxy-3-cyclohexene-1-methanol, with the process for obtaining the same. which consists of the preparation of (-)-(6,6-dimethylbicyclo[3.1.1.] ept-2-ene-2-ethanol epoxide, followed by hydration of the above compound. Finally, this invention comprises the pharmaceutical compositions con- taming the compound of formula (I) which have a mucosecretolytic pharmacological activity.
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| description | A novel derivative of (-)-6,6-dimethylbicyclo [3.1.1] ept-2- ene-2-ethanol (J.P. Bain. J. Am. Chem. Soc. 1946, Vol. 68, page 638) is disclosed. The patent composition is marketed e.g. under the name nopol, v. The Aldrich-Europe Catalog Handbook of Fine Chemicals, item 3160-5 nopol 98% 128-50-7.The object of the present invention is the compound of formula (I) : 4-(2-hydroxyethyl) -a a dimethyl-5-hydroxy-3-cyclohexene-1-methanol, with the process for obtaining the same. which consists of the preparation of (-)-(6,6-dimethylbicyclo[3.1.1.] ept-2-ene-2-ethanol epoxide, followed by hydration of the above compound. Finally, this invention comprises the pharmaceutical compositions con- taming the compound of formula (I) which have a mucosecretolytic pharmacological activity. |
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| title | Patent AT-E40103-T1: [Translated] CYCLOHEXENEMETHANOL DERIVATIVE WITH MUCOSECRETOLYTIC ACTIVITY, ITS MANUFACTURING PROCESS AND PHARMACEUTICAL COMPOSITIONS CONTAINING IT. |
