Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS
The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of:a) at least one neutral diacyl lipid and/or at least one tocopherol;b) at least one phospholipid;c) at least one biocompatible, oxygen containing, low viscosity organic solvent;wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.
Complete Metadata
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| accessLevel | public |
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[
"009:25"
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"fn": "NIH/NCBI Data Team",
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| description | The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of:a) at least one neutral diacyl lipid and/or at least one tocopherol;b) at least one phospholipid;c) at least one biocompatible, oxygen containing, low viscosity organic solvent;wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament. |
| distribution |
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"title": "Official Data Source",
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"description": "Access the complete Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS on the official website.",
"downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401054-T1"
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|
| identifier | https://healthdata.gov/api/views/c9ud-wvv6 |
| issued | 2025-09-05 |
| keyword |
[
"chemistry",
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| landingPage | https://healthdata.gov/d/c9ud-wvv6 |
| modified | 2025-09-06 |
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| publisher |
{
"name": "National Center for Biotechnology Information (NCBI)",
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| theme |
[
"NIH"
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|
| title | Patent AT-E401054-T1: [Translated] LIQUID DEPOSIT FORMULATIONS |
