Patent AT-E401067-T1: [Translated] USE OF 4-HYDROXYTAMOXIFEN IN THE PRODUCTION OF A MEDICATION FOR THE TREATMENT OF GYNECOMASTIA
The present invention provides methods for treating and preventing gynecomastia by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogenic effect. In patients with gynecomastia, this reduces the effective estrogen-androgen ratio in the breast tissue, thereby reducing ductal proliferation, epithelial and stromal hyperplasia, and pain. In patients at risk for developing gynecomastia, 4-hydroxy tamoxifen's anti-estrogenic effect prevents tissue proliferation and its accompanying pain.
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"009:25"
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{
"fn": "NIH/NCBI Data Team",
"@type": "vcard:Contact",
"hasEmail": "mailto:info@ncbi.nlm.nih.gov"
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|
| description | The present invention provides methods for treating and preventing gynecomastia by administering 4-hydroxy tamoxifen to a patient. When percutaneously administered to a patient's breasts, 4-hydroxy tamoxifen concentrates locally, and exerts an anti-estrogenic effect. In patients with gynecomastia, this reduces the effective estrogen-androgen ratio in the breast tissue, thereby reducing ductal proliferation, epithelial and stromal hyperplasia, and pain. In patients at risk for developing gynecomastia, 4-hydroxy tamoxifen's anti-estrogenic effect prevents tissue proliferation and its accompanying pain. |
| distribution |
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"title": "Official Data Source",
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"description": "Access the complete Patent AT-E401067-T1: [Translated] USE OF 4-HYDROXYTAMOXIFEN IN THE PRODUCTION OF A MEDICATION FOR THE TREATMENT OF GYNECOMASTIA on the official website.",
"downloadURL": "https://pubchem.ncbi.nlm.nih.gov/patent/AT-E401067-T1"
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|
| identifier | https://healthdata.gov/api/views/hmvn-m5vd |
| issued | 2025-09-05 |
| keyword |
[
"chemistry",
"innovation",
"patent",
"pubchem",
"research"
]
|
| landingPage | https://healthdata.gov/d/hmvn-m5vd |
| modified | 2025-09-06 |
| programCode |
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| publisher |
{
"name": "National Center for Biotechnology Information (NCBI)",
"@type": "org:Organization"
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|
| theme |
[
"NIH"
]
|
| title | Patent AT-E401067-T1: [Translated] USE OF 4-HYDROXYTAMOXIFEN IN THE PRODUCTION OF A MEDICATION FOR THE TREATMENT OF GYNECOMASTIA |
