Patent AT-E40108-T1: [Translated] PROCESSES FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE ARYLOXYPROPANOLAMINE COMPOUNDS.
(57) A process for the preparation of an aryloxypropanolamine of the formulawherein Ar is a carbocyclic or heterocyclic aromatic group and R is an alkyl or substituted alkyl group having 1 to 6 carbon atoms, characterized in subjecting a compound of the formulato oxidative deavage to a dialdehyde of the formulawhich is then made subject to reduction, amination, acetal hydrolysis, and, where required, removal of a nitrogen protective group, to the formation of a compound of formula I, or an acid accition salt thereof, a compound of formula II and the preparation thereof from mannitol.
Complete Metadata
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| description | (57) A process for the preparation of an aryloxypropanolamine of the formulawherein Ar is a carbocyclic or heterocyclic aromatic group and R is an alkyl or substituted alkyl group having 1 to 6 carbon atoms, characterized in subjecting a compound of the formulato oxidative deavage to a dialdehyde of the formulawhich is then made subject to reduction, amination, acetal hydrolysis, and, where required, removal of a nitrogen protective group, to the formation of a compound of formula I, or an acid accition salt thereof, a compound of formula II and the preparation thereof from mannitol. |
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| identifier | https://healthdata.gov/api/views/q94w-dfiv |
| issued | 2025-09-05 |
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| modified | 2025-09-06 |
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| title | Patent AT-E40108-T1: [Translated] PROCESSES FOR THE PREPARATION OF PHARMACEUTICALLY ACTIVE ARYLOXYPROPANOLAMINE COMPOUNDS. |
