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Patent AT-E401323-T1: [Translated] SYNTHESIS OF 2-BUTYL-3-(2'-(1-TRITYL-1H-TETRAZOLE- 5-YL)BIPHENYL-4-YL)-1,3-DIAZASPIRO-4,4 -NONEN-4-ONE

Published by National Center for Biotechnology Information (NCBI) | U.S. Department of Health & Human Services | Metadata Last Checked: September 07, 2025 | Last Modified: 2025-09-06
Provided is a novel method of making 2-butyl-3-[[2'(1-trityl-1H-tetrazol-5-yl)biphen-4-yl]methyl]-1,3-diazaspiro[4.4]non-1-ene-4-one, which can be converted to irbesartan. Also provided are methods of making irbesartan.

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