Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands
G-protein-coupled receptors (GPCRs) are the largest and most diverse family of transmembrane receptors. A pylogenetic analysis shows the overall relationship of 277 human GPCRs. An emphasis on receptors with no identified natural ligand may prove valuable for identification of the ligands of 'orphan' receptors.
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"009:25"
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|
| contactPoint |
{
"fn": "NIH",
"@type": "vcard:Contact",
"hasEmail": "mailto:info@nih.gov"
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|
| description | G-protein-coupled receptors (GPCRs) are the largest and most diverse family of transmembrane receptors. A pylogenetic analysis shows the overall relationship of 277 human GPCRs. An emphasis on receptors with no identified natural ligand may prove valuable for identification of the ligands of 'orphan' receptors. |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "Official Government Data Source",
"mediaType": "text/html",
"description": "Visit the original government dataset for complete information, documentation, and data access.",
"downloadURL": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC133447/"
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|
| identifier | https://healthdata.gov/api/views/xcyy-6mx7 |
| issued | 2025-07-14 |
| keyword |
[
"g-protein-coupled-receptors",
"ligand-prediction",
"nih",
"orphan-receptors",
"phylogenetic-analysis"
]
|
| landingPage | https://healthdata.gov/d/xcyy-6mx7 |
| modified | 2025-09-06 |
| programCode |
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"009:033"
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|
| publisher |
{
"name": "National Institutes of Health",
"@type": "org:Organization"
}
|
| theme |
[
"NIH"
]
|
| title | Phylogenetic analysis of 277 human G-protein-coupled receptors as a tool for the prediction of orphan receptor ligands |
