Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus
An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs.
Resources in this dataset:
Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus
File Name: TMPRSS2 dataset.xlsx
Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.
Complete Metadata
| @type | dcat:Dataset |
|---|---|
| accessLevel | public |
| bureauCode |
[
"005:18"
]
|
| contactPoint |
{
"fn": "Baker, Amy L.",
"hasEmail": "mailto:amy.l.baker@usda.gov"
}
|
| description | <p>An experimental challenge of Influenza A virus in genetically modified TMPRSS2 knockout pigs.</p> <p>Resources in this dataset:</p> <ul> <li>Resource Title: Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus File Name: TMPRSS2 dataset.xlsx Resource Description: Supporting data for: Nasal shedding of A/swine/Iowa/A02524480/2020 (IA/20) H1N1 by virus titration on cell culture or qRT-PCR; Infection of IA/20 H1N1 in WT and TMPRSS2-/- pigs; Immunohistochemical (IHC) staining of Influenza A virus nucleoprotein; Cytokine and chemokine panel performed on bronchioalveolar lavage fluid.</li> </ul><p></p> |
| distribution |
[
{
"@type": "dcat:Distribution",
"title": "TMPRSS2 dataset.xlsx",
"format": "xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://ndownloader.figshare.com/files/43757148"
}
]
|
| identifier | 10.15482/USDA.ADC/1529793 |
| keyword |
[
"ARS",
"Influenza A virus",
"NP103",
"Swine",
"TMPRSS2",
"data.gov",
"disease resistance"
]
|
| license | https://www.usa.gov/publicdomain/label/1.0/ |
| modified | 2025-11-21 |
| programCode |
[
"005:040"
]
|
| publisher |
{
"name": "Agricultural Research Service",
"@type": "org:Organization"
}
|
| spatial |
"{"type": "Point", "coordinates": [-93.617248535156, 42.044002396934]}"
|
| temporal | 2022-10-01/2023-05-31 |
| title | Pigs lacking TMPRSS2 displayed fewer lung lesions and reduced inflammatory response when infected with Influenza A virus |
