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Polychlorinated Biphenyls Mixtures Similarity Tool (MiST)

Published by U.S. EPA Office of Research and Development (ORD) | U.S. Environmental Protection Agency | Metadata Last Checked: August 02, 2025 | Last Modified: 2022-03-24
The PCB Mixtures Similarity Tool (MiST) is an Excel-based tool that automates the process for determining whether two PCB mixtures are "sufficiently similar". Humans are exposed to complex mixtures of PCBs in the environment; however, only a small subset of PCB mixtures has been tested for toxicity. MiST was developed as a tool for risk assessors to evaluate how dose-response information for tested PCB mixtures may serve as a surrogate when assessing untested mixtures found in the environment.

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