Report on Evaluation of the Interaction-based Hazard Index Formula with Data on Trihalomethanes
The endpoints selected for evaluation of the HIINT formula were percent relative liver weight of mice (PcLiv) and the logarithm of ALT [Log(ALT)], where the log transformation was used to help stabilize the increases in variance with dose found in the ALT dataset.
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Tony McDonald",
"hasEmail": "mailto:mcdonald.tony@epa.gov"
}
|
| description | The endpoints selected for evaluation of the HIINT formula were percent relative liver weight of mice (PcLiv) and the logarithm of ALT [Log(ALT)], where the log transformation was used to help stabilize the increases in variance with dose found in the ALT dataset. |
| distribution |
[
{
"title": "Appendix A-9_Interact-HI-THMs_2021-01-31.docx",
"mediaType": "application/vnd.openxmlformats-officedocument.wordprocessingml.document",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1531675/Appendix%20A-9_Interact-HI-THMs_2021-01-31.docx"
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|
| identifier | https://doi.org/10.23719/1531675 |
| keyword |
[
"Binary Interaction Weight-of-Evidence",
"Dose Additivity",
"Hazard Index",
"Mixture Effective Dose Estimation",
"chemical Mixtures Risk Assessment",
"chemical mixtures",
"dose addition",
"interactions"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2024-04-23 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
null
|
| rights |
null
|
| title | Report on Evaluation of the Interaction-based Hazard Index Formula with Data on Trihalomethanes |
