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Reproducible changes in gut microbiome reveal a shift in microbial and host metabolism during spaceflight

Published by Open Science Data Repository | National Aeronautics and Space Administration | Metadata Last Checked: August 31, 2025 | Last Modified: 2025-08-21
Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-System. NASA NRA: NRA NNH14ZTT002N). As part of the study, we requested and received samples from RR1. We generated 16S rRNA gene amplicon sequence data from DNA extracted from fecal samples, and compared these data to similar data generated on shuttle mission STS-135 and from ground-based studies of radiation. We assessed effect of flight conditions and radiation.

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