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Rodent Research-1 (RR1) National Lab Validation Flight: Mouse liver transcriptomic, proteomic, epigenomic and histology data

Published by Open Science Data Repository | National Aeronautics and Space Administration | Metadata Last Checked: August 31, 2025 | Last Modified: 2025-08-21
The Rodent Reasearch-1 National Lab (RR-1 CASIS) experiment was performed to study the effect of microgravity on muscle wasting. RNA, DNA, and protein were purified from RR-1 CASIS (the Center for the Advancement of Science in Space) liver samples. Groups included: Flight (FLT) dissected on-orbit (21 or 22 days after launch); age-matched Ground Controls (GC); and Basal Controls (BC, euthanized at time of launch). RNA-Seq, whole genome BS-Seq (bisulfite sequencing) and proteomic expression profiling were performed.

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