Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe
We used systematic evidence map methods to summarize the available epidemiological and animal bioassay evidence for an expanded set of ~15,000 PFAS that were identified as PFAS by EPA's Center for Computational Toxicology and Exposure (CCTE). This work is a continuation of our previous 2022 and 2024 SEMs that inventoried evidence on a separate set of ~500 PFAS (Carlson et al, 2022, https://doi.org/10.1289/EHP10343; Radke et al, 2022, https://doi.org/10.1289/EHP11185; Carlson et al., 2024; https://doi.org/10.1289/EHP14191) and a 2023 evidence map on an additional 345 PFAS (Shirke et al. 2024, https://doi.org/10.1289/EHP13423 ). The comprehensive PFAS dashboard includes evidence identified from our past SEMs and completed US EPA assessments.
This dataset is associated with the following publication:
Shirke, A., E. Radke, R. Jones, B. Allen, C. Lin, A. Ross, N. Vetter, C. Lemeris, p. hartman, S. Eftim, A. Varghese, R. Blain, H. Hubbard, A. Williams, K. Thayer, and L. Carlson. Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 0(0): 1-45, (2025).
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Laura Carlson",
"hasEmail": "mailto:carlson.laura@epa.gov"
}
|
| description | We used systematic evidence map methods to summarize the available epidemiological and animal bioassay evidence for an expanded set of ~15,000 PFAS that were identified as PFAS by EPA's Center for Computational Toxicology and Exposure (CCTE). This work is a continuation of our previous 2022 and 2024 SEMs that inventoried evidence on a separate set of ~500 PFAS (Carlson et al, 2022, https://doi.org/10.1289/EHP10343; Radke et al, 2022, https://doi.org/10.1289/EHP11185; Carlson et al., 2024; https://doi.org/10.1289/EHP14191) and a 2023 evidence map on an additional 345 PFAS (Shirke et al. 2024, https://doi.org/10.1289/EHP13423 ). The comprehensive PFAS dashboard includes evidence identified from our past SEMs and completed US EPA assessments. This dataset is associated with the following publication: Shirke, A., E. Radke, R. Jones, B. Allen, C. Lin, A. Ross, N. Vetter, C. Lemeris, p. hartman, S. Eftim, A. Varghese, R. Blain, H. Hubbard, A. Williams, K. Thayer, and L. Carlson. Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe. ENVIRONMENTAL HEALTH PERSPECTIVES. National Institute of Environmental Health Sciences (NIEHS), Research Triangle Park, NC, USA, 0(0): 1-45, (2025). |
| distribution |
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"title": "https://hawc.epa.gov/assessment/100500347/",
"accessURL": "https://hawc.epa.gov/assessment/100500347/"
},
{
"title": "https://heronet.epa.gov/heronet/index.cfm/project/page/project_id/4214",
"accessURL": "https://heronet.epa.gov/heronet/index.cfm/project/page/project_id/4214"
},
{
"title": "https://public.tableau.com/app/profile/literature.inventory/viz/ComprehensivePFASEvidenceMapVisualizations/ReadMe",
"accessURL": "https://public.tableau.com/app/profile/literature.inventory/viz/ComprehensivePFASEvidenceMapVisualizations/ReadMe"
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"title": "https://public.tableau.com/app/profile/literature.inventory/viz/PFASUniverseEvidenceMapVisualizations_17249628281260/ReadMe",
"accessURL": "https://public.tableau.com/app/profile/literature.inventory/viz/PFASUniverseEvidenceMapVisualizations_17249628281260/ReadMe"
},
{
"title": "PFAS Universe Supplemental A Data_final.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1531798/PFAS%20Universe%20Supplemental%20A%20Data_final.xlsx"
},
{
"title": "PFAS Universe Supplemental B Prioritization Datasets final.xlsx",
"mediaType": "application/vnd.openxmlformats-officedocument.spreadsheetml.sheet",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1531798/PFAS%20Universe%20Supplemental%20B%20Prioritization%20Datasets%20final.xlsx"
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]
|
| identifier | https://doi.org/10.23719/1531798 |
| keyword |
[
"PFAS",
"Risk Assessment",
"evidence map",
"hazard identification"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2024-10-28 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
[
"https://doi.org/10.1289/ehp16952"
]
|
| rights |
null
|
| title | Systematic Evidence Map for the Per- and Polyfluoroalkyl Substances (PFAS) Universe |
