The relationship between FV Leiden and pulmonary embolism
Pulmonary embolism (PE) is one of the leading causes of in-patient hospital deaths. As a consequence, the identification of hemostatic variables that could identify those at risk would be important in reducing mortality. It has previously been thought that deep vein thrombosis and PE are a single disease entity and would, therefore, have the same risk factors. This view is changing, however, with the realization that the prevalence of FV Leiden, a recognized genetic risk factor for deep vein thrombosis, may be a 'milder' genetic risk factor for PE. These observations suggest that PE is not only associated with a different set of risk factors, but may be reflective of a different clot structure.
Complete Metadata
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| description | Pulmonary embolism (PE) is one of the leading causes of in-patient hospital deaths. As a consequence, the identification of hemostatic variables that could identify those at risk would be important in reducing mortality. It has previously been thought that deep vein thrombosis and PE are a single disease entity and would, therefore, have the same risk factors. This view is changing, however, with the realization that the prevalence of FV Leiden, a recognized genetic risk factor for deep vein thrombosis, may be a 'milder' genetic risk factor for PE. These observations suggest that PE is not only associated with a different set of risk factors, but may be reflective of a different clot structure. |
| distribution |
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| identifier | https://healthdata.gov/api/views/r3q5-rtxa |
| issued | 2025-07-14 |
| keyword |
[
"factor-v-leiden",
"genetic-risk-factors",
"nih",
"pulmonary-embolism",
"venous-thromboembolism"
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| modified | 2025-09-06 |
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| publisher |
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|
| theme |
[
"NIH"
]
|
| title | The relationship between FV Leiden and pulmonary embolism |
