Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract.
METADATA
OUTLINE
SHEET 1 STUDY INFORMATION
SHEET 2 RANDOM ASSISNMENT OF PREGNANT RATS TO TREATMENT GROUPS
SHEER 3 MATERNAL WEIGHT AND WEIGHT GAIN DURING DOSING and fetal DATA
RAW DATA
RESULTS
PREDICTIONS OF DOSE ADDITIVITY
SHEET 4 TESTOSTERONE (T PROD) DATA
RAW DATA
SAS INPUT FILES
TREATMENT EFFECTS
SHEET 5 CUSTOM GENE (mRNA) SAS INPUT FILE WITH SAS STATEMENTS AND RQW DATA
SHEET 6 RESULTS FROM STATISTICAL ANALYSIS OF CUSTOM ARRAY mRNA DATA
CUSTOM ARRAY: LIST OF GENES AND GENE DESCRIPTIONS
SHEET 7 PREDICTION MODELS OF TESTOSTERONE PRODUCTION REDUCTIONS AND REPRODUCTIVE EFFECTS OF IN UTERO PHTHALATE EXPOSURE
SHEET 8 TREATMENT EFFECTS PREDICTED FROM THE TESTOSTERONE PREDICTION MODELS
COMPARISON OF THE PREDICTED EFFECTS OF THE DBP+DINP MIXTURE WITH OBSERVED EFFECTS OF THE REFERENCE CHEMICAL (DBP) AT EQUIVALENT DOSES, ASSUMING DOSE ADDITIVITY.
This dataset is associated with the following publication:
Gray, L., C. Lambright, N. Evans, J. Ford, and J. Conley. Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract.. Current Research in Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 7: 100180, (2024).
Complete Metadata
| accessLevel | public |
|---|---|
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[
"020:00"
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| contactPoint |
{
"fn": "Leon Gray",
"hasEmail": "mailto:gray.earl@epa.gov"
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| description | METADATA OUTLINE SHEET 1 STUDY INFORMATION SHEET 2 RANDOM ASSISNMENT OF PREGNANT RATS TO TREATMENT GROUPS SHEER 3 MATERNAL WEIGHT AND WEIGHT GAIN DURING DOSING and fetal DATA RAW DATA RESULTS PREDICTIONS OF DOSE ADDITIVITY SHEET 4 TESTOSTERONE (T PROD) DATA RAW DATA SAS INPUT FILES TREATMENT EFFECTS SHEET 5 CUSTOM GENE (mRNA) SAS INPUT FILE WITH SAS STATEMENTS AND RQW DATA SHEET 6 RESULTS FROM STATISTICAL ANALYSIS OF CUSTOM ARRAY mRNA DATA CUSTOM ARRAY: LIST OF GENES AND GENE DESCRIPTIONS SHEET 7 PREDICTION MODELS OF TESTOSTERONE PRODUCTION REDUCTIONS AND REPRODUCTIVE EFFECTS OF IN UTERO PHTHALATE EXPOSURE SHEET 8 TREATMENT EFFECTS PREDICTED FROM THE TESTOSTERONE PREDICTION MODELS COMPARISON OF THE PREDICTED EFFECTS OF THE DBP+DINP MIXTURE WITH OBSERVED EFFECTS OF THE REFERENCE CHEMICAL (DBP) AT EQUIVALENT DOSES, ASSUMING DOSE ADDITIVITY. This dataset is associated with the following publication: Gray, L., C. Lambright, N. Evans, J. Ford, and J. Conley. Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract.. Current Research in Toxicology. Elsevier B.V., Amsterdam, NETHERLANDS, 7: 100180, (2024). |
| distribution |
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"title": "DBP DINP MIX paper METADATA FOR PUBLICATION.xls",
"mediaType": "application/vnd.ms-excel",
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| identifier | https://doi.org/10.23719/1530554 |
| keyword |
[
"Risk Assessment"
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| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2024-03-27 |
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| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
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| references |
[
"https://doi.org/10.1016/j.crtox.2024.100180",
"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11239482"
]
|
| rights |
null
|
| title | Using Targeted Fetal Rat Testis Genomic and Endocrine Alterations to Predict the Effects of a Phthalate Mixture on the Male Reproductive Tract. |
