Found 7 datasets matching filters.
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The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist activity. Active compounds were...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
HT-H295R data was downloaded using the ToxCast pipeline (tcpl) R package and is publicly available. Multi-concentration level 0 data from invitrodb (version 3.1) were downloaded and converted from...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on predicting in vivo...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
The tcpl package provides a set of tools for processing and modeling high-throughput and high-content chemical screening data. This dataset is associated with the following publication: Filer,...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
This supplemental material describes two sets of methods; first, it briefly describes the process used to create the EPA’s LitDB database, and second, it describes how a subset of records were...
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Table S1. All chemicals and AC50 from invitrodb v3 for human FACTORIAL-TRANS assay endpoints. Table S2. Agreement with OECD reference AR agonists. Table S3. Agreement with OECD reference ER...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Screening certain environmental chemicals for their ability to interact with endocrine targets, including the androgen receptor (AR), is an important global concern. We previously developed a...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02
