Found 18 datasets matching filters.
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This is a new, open, and transparent database of toxicokinetic data supporting EPA decision making. The database has already become the basis of research efforts within EPA to improve HTTK...
Search relevance: 1.00 | Views last month: 30 | Published on: 2025-08-02 -
Table S1: Tox21 IDs mapped to NCGC IDs, PubChem IDs, and DSSTox IDs, and indicating NCATS, NTP and EPA partner library associations (date stamped February 24, 2020). Table S2: DSSTox TOX21SL list...
Search relevance: 1.00 | Views last month: 6 | Published on: 2025-08-02 -
Background It is generally assumed that the tissue exchange of antibiotics is flow limited (complete equilibration between the capillary and the tissue water). This assumption may not be...
Search relevance: 1.00 | Views last month: 4 | Published on: 2025-09-07 -
In this study, a major effort was undertaken to compile a large genotoxicity dataset (54,805 records for 9299 substances) from several public sources (e.g., TOXNET, COSMOS, eChemPortal). The names...
Search relevance: 1.00 | Views last month: 3 | Published on: 2025-08-02 -
Background This paper assess the relationship between the quantity of three anti-seizure medications in hair and the color of the analyzed hair, while controlling for the effects of...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-09-07 -
Here are all of the data files used for this manuscript. Please note that this is all published data. Imran Shah 1.1060+ Chemicals and Chemical controls 2. Chemical descriptors (chm): 2048 Morgan...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have been obtained from relatively...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Read-across (RAX) is a widely used data gap filling approach and the authors have developed a data-driven tool, called GenRA, to support expert-driven RAX. This work describes a stand-alone Python...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Japanese quail (Coturnix japonica) were orally dosed with pesticide-treated or control-untreated wheat seeds. Pesticide treated wheat seeds were analytically verified for active ingredients of...
Search relevance: 1.00 | Views last month: 1 | Published on: 2026-03-03 -
Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-09-07 -
File contains raw data collected on body and organ weights of mice given PFBS and body burden of the chemical after intervals of several hours, as well as expression of liver candidate genes for...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
Anatoxin levels in mouse tissues after a single exposure and collected at various timepoints
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-10-23 -
Acute rat oral toxicity lethality data files, processed prediction files from 2 expert systems. This dataset is associated with the following publication: Nelms, M., A. Karmaus, and G....
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
An effort was made to derive new inhalation TTC values using the EPA’s Toxicity Values database, ToxValDB. A total of 4703 substances captured in ToxValDB were assigned into their respective TTC...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Background The application of physiologically based pharmacokinetic models (PBPK) to human studies has been limited by the lack of the detailed organ information that is required for...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07 -
This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion to inhalation exposure for...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-30 -
Mouse assays. This dataset is associated with the following publication: Diamond, G., K. Bradham, and D. Thomas. Evaluating the Mouse Model for Estimation of Arsenic Bioavailability: Comparison...
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-08-02 -
Pharmacology of the critically ill
Search relevance: 1.00 | Views last month: 0 | Published on: 2025-09-07
