Model Code Associated with "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors"
This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors." The model code is written in R with a .model file written in the MCSim language. The inhalation pharmacokinetic model builds on a previous publication of Bernstein et al., "A Model Template Approach for Rapid Evaluation and Application of Physiologically Based Pharmacokinetic Models for Use in Human Health Risk Assessments: A Case Study on Per- and Polyfluoroalkyl Substances" https://doi.org/10.1093/toxsci/kfab063
Complete Metadata
| accessLevel | public |
|---|---|
| bureauCode |
[
"020:00"
]
|
| contactPoint |
{
"fn": "Michael Dzierlenga",
"hasEmail": "mailto:dzierlenga.michael@epa.gov"
}
|
| description | This ScienceHub entry contains a zip file with the pharmacokinetic modeling code used for the linked publication, "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors." The model code is written in R with a .model file written in the MCSim language. The inhalation pharmacokinetic model builds on a previous publication of Bernstein et al., "A Model Template Approach for Rapid Evaluation and Application of Physiologically Based Pharmacokinetic Models for Use in Human Health Risk Assessments: A Case Study on Per- and Polyfluoroalkyl Substances" https://doi.org/10.1093/toxsci/kfab063 |
| distribution |
[
{
"title": "PFAS_inhalation_PBPK_template.zip",
"mediaType": "application/zip",
"downloadURL": "https://pasteur.epa.gov/uploads/10.23719/1532470/PFAS_inhalation_PBPK_template.zip"
}
]
|
| identifier | https://doi.org/10.23719/1532470 |
| keyword |
[
"PFAS",
"Risk Assessment",
"inhalation",
"pharmacokinetics",
"toxicokinetics"
]
|
| license | https://pasteur.epa.gov/license/sciencehub-license.html |
| modified | 2025-08-21 |
| programCode |
[
"020:000"
]
|
| publisher |
{
"name": "U.S. EPA Office of Research and Development (ORD)",
"subOrganizationOf": {
"name": "U.S. Environmental Protection Agency",
"subOrganizationOf": {
"name": "U.S. Government"
}
}
}
|
| references |
null
|
| rights |
null
|
| title | Model Code Associated with "Challenges for extrapolation of risk from ingestion to inhalation exposure for per- and polyfluorinated alkyl acids and their precursors" |
