Found 57 datasets matching filters.
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Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from over 1,000 public sources on...
Search relevance: 1.00 | Views last month: 14 | Published on: 2025-07-31 -
The Chemical and Product Categories database (CPCat) catalogs the use of over 40,000 chemicals and their presence in different consumer products. The chemical use information is compiled from...
Search relevance: 1.00 | Views last month: 8 | Published on: 2025-07-31 -
Data from a large-scale modeling project called CERAPP (Collaborative Estrogen Receptor Activity Prediction Project) demonstrating using predictive computational models on high-throughput...
Search relevance: 1.00 | Views last month: 8 | Published on: 2025-08-02 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 1.00 | Views last month: 6 | Published on: 2025-07-31 -
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been...
Search relevance: 1.00 | Views last month: 6 | Published on: 2025-08-02 -
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
Search relevance: 1.00 | Views last month: 3 | Published on: 2025-08-02 -
The JRC dataset (doi: 10.1016/j.tiv.2016.07.014) includes reported outcomes in chemico, in vitro and in vivo tests for skin sensitisation. The Tox21 dataset was downloaded from the EPA CompTox...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
This manuscript describes development of a novel tool called Tox21BodyMap. This tool is designed to map biological assay data onto organs of the human body, facilitating predictions between...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
The Tox21 chemical library (8,305 unique structures) was screened in a quantitative high-throughput, cell-based reporter gene assay for TR agonist or antagonist activity. Active compounds were...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
Thousands of chemicals are directly added to or come in contact with food, many of which have undergone little to no toxicological evaluation. The landscape of the food-relevant chemical universe...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
The Exposure Forecaster Database (ExpoCastDB) is EPA's database for aggregating chemical exposure information and can be used to help with chemical exposure predictions. The database currently...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-07-31 -
Gene expression data from the Fluidigm qRT-PCR arrays was analyzed in R (v3.6.1; R Foundation for Statistical Computing, 2019). Prior to processing through the tcpl package, each qRT-PCR primer...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high throughput, in...
Search relevance: 1.00 | Views last month: 2 | Published on: 2025-08-02 -
Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") as in Pearce et al. (2017) . Chemical-specific in vitro data have been obtained from relatively...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
In the present study, we adapted an existing phenotypic profiling assay (“Cell Painting”, (Bray et al., 2016)) to be compatible with in-house microfluidics capabilities for 384-well culture...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
A data set of 500 chemicals evaluated for their ability to induce cleft palate in animal prenatal developmental studies was compiled from Toxicity Reference Database and the biomedical literature,...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
httk: High-Throughput Toxicokinetics Functions and data tables for simulation and statistical analysis of chemical toxicokinetics ("TK") using data obtained from relatively high throughput, in...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
HT-H295R data was downloaded using the ToxCast pipeline (tcpl) R package and is publicly available. Multi-concentration level 0 data from invitrodb (version 3.1) were downloaded and converted from...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-08-02 -
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It helps to build a data...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-07-31 -
EPA researchers have been using advances in computational toxicology to address lack of data on the thousands of chemicals. EPA released chemical data on 1,800 chemicals. The 1,800 chemicals were...
Search relevance: 1.00 | Views last month: 1 | Published on: 2025-07-31
