• Organization: U.S. Environmental Protection Agency
• Updated: 2019-07-17

Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a simple AOP network...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-02-23

Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-03-17

Exemestane is a prescription medication available as 25 mg oral tablets, manufactured by Breckenridge Pharmaceutical, Inc. It belongs to the aromatase inhibitor class and is used to treat hormone...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2018-12-13

There is significant concern regarding potential impairment of fish reproduction associated with endocrine disrupting chemicals. Aromatase (CYP19) is a steroidogenic enzyme involved in the...

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• Organization: U.S. Environmental Protection Agency
• Updated: 2017-09-22

computational chemistry data (very complex; need to be an expert to understand and use. This dataset is associated with the following publication: Lee, S., and M. Barron. 3D-QSAR Study of...

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