Found 9 datasets matching "EDSP".
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This dataset provides measured in vitro intrinsic clearance rates for 54 chemicals tested using isolated hepatocytes from humans, rats, and rainbow trout. The test chemicals were selected to...
Search relevance: 45.44 | Views last month: 0 -
In response to various legislative mandates the United States Environmental Protection Agency (USEPA) formed its Endocrine Disruptor Screening Program (EDSP), which in turn, implemented a tiered...
Search relevance: 41.09 | Views last month: 0 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 37.60 | Views last month: 1 -
A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
Search relevance: 36.22 | Views last month: 0 -
These data are represented in the tables and graphs in the journal article, Antiandrogenic effects following multiple life stage exposure to the fungicide prochloraz in Xenopus laevis by JT...
Search relevance: 32.22 | Views last month: 0 -
These data are from two studies conducted to evaluate the performance of the draft Larval Amphibian Growth and Development Assay for incorporation into the U.S. EPA's Endocrine Disruptor Screening...
Search relevance: 32.05 | Views last month: 0 -
Data and supplemental files from COMPARA (A large-scale modeling project). COMPARA combined multiple models developed in collaboration with modelers and computational toxicology scientists from 25...
Search relevance: 31.07 | Views last month: 0 -
Five chemicals [2-ethylhexyl 4-hydroxybenzoate (2-EHHB), 4-nonylphenol-branched (4-NP), 4-tert-octylphenol (4-OP), benzyl butyl phthalate (BBP) and dibutyl phthalate (DBP) were subjected to a...
Search relevance: 30.23 | Views last month: 1 -
Evaluation of multigenerational effects of 2-ethylhexyl 4-hydroxybenzoate in Japanese medaka Abstract The Japanese medaka (Oryzias latipes) extended one-generation reproduction test (MEOGRT)...
Search relevance: 29.99 | Views last month: 0