Found 13 datasets matching "Predictive Toxicity".
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Dataset for Baker, et al., Identifying candidate reference chemicals for in vitro testing of the retinoid pathway for predictive developmental toxicity, published in journal Altex,...
Search relevance: 186.86 | Views last month: 0 -
In an effort to address a major challenge in chemical safety assessment, alternative approaches for characterizing systemic effect levels, a predictive model was developed. Systemic effect levels...
Search relevance: 80.92 | Views last month: 0 -
The Distributed Structure Searchable Toxicity (DSSTox) online resource provides high quality chemical structures and annotations in association with toxicity data. It helps to build a data...
Search relevance: 57.73 | Views last month: 1 -
This dataset includes data used to generate Figures 4C, 5B, 5C, and 5D in Tal et al. Screening for angiogenic inhibitors in zebrafish to evaluate a predictive model for developmental vascular...
Search relevance: 57.68 | Views last month: 0 -
ToxRefDB comprises information from over fifty years of in vivo toxicity data. The database includes information for over 1000 chemicals, and is being used as a primary source of data for...
Search relevance: 52.20 | Views last month: 7 -
The data used in this analysis was obtained from published literature and available through the high-throughput toxicokinetic (HTTK) R package. The dataset consists of 1486 chemicals that span a...
Search relevance: 46.19 | Views last month: 0 -
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that can generate...
Search relevance: 45.84 | Views last month: 0 -
Anthropogenic activities introduce complex mixtures into aquatic environments, necessitating the evaluation of mixture toxicity during ecological risk assessments. There are many new approach...
Search relevance: 44.04 | Views last month: 0 -
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on predicting in vivo...
Search relevance: 42.61 | Views last month: 0 -
Morphogenetic events are driven by cell-generated physical forces and complex cellular dynamics. To improve our capacity to predict developmental effects from cellular alterations, we built a...
Search relevance: 42.57 | Views last month: 0 -
Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing challenge with several efforts...
Search relevance: 40.05 | Views last month: 0 -
Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a simple AOP network...
Search relevance: 38.31 | Views last month: 0 -
Proportional response addition (Prop-RA), a model for predicting response from chemical mixture exposure, is demonstrated, and evaluated by statistically evaluating data on all possible binary...
Search relevance: 30.23 | Views last month: 1
