Found 44 datasets matching "arthritis-inflammation".
-
The transcription factor NF-κB has been well recognized as a pivotal regulator of inflammation in rheumatoid arthritis (RA), but recent developments revealed a broad involvement of NF-κB in other...
Search relevance: 209.68 | Views last month: 0 -
We investigated the role of Fcγ receptors (FcγRs) on synovial macrophages in immune-complex-mediated arthritis (ICA). ICA elicited in knee joints of C57BL/6 mice caused a short-lasting, florid...
Search relevance: 194.18 | Views last month: 0 -
This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung. Neovascularisation is a fundamental process...
Search relevance: 125.03 | Views last month: 0 -
Tissue factor (TF) is a transmembrane glycoprotein and the main triggering element of blood coagulation. TF expression on monocytes and endothelial cells is induced by exposure to endotoxin, tumor...
Search relevance: 122.14 | Views last month: 0 -
Our results show that cytokines derived from macrophages play an important role in pathogenesis of arthritis triggered by CpG oligodinucleotide (CpG ODN). IL-12 is in this respect an important...
Search relevance: 121.15 | Views last month: 0 -
Rheumatoid arthritis represents an excellent model in which to gain insights into the local and systemic effects of joint inflammation on skeletal tissues. Three forms of bone disease have...
Search relevance: 116.03 | Views last month: 0 -
The abundance and activation of macrophages in the inflamed synovial membrane/pannus significantly correlates with the severity of rheumatoid arthritis (RA). Although unlikely to be the...
Search relevance: 112.07 | Views last month: 0 -
A chance observation has led to the development of a new murine model for inflammatory arthritis. Arthritis is induced, and transferred, by T-cell-dependent antibodies to glucose-6-phosphate...
Search relevance: 74.01 | Views last month: 0 -
There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In the present study, we examined...
Search relevance: 72.12 | Views last month: 0 -
To determine whether IL-4 is therapeutic in treating established experimental arthritis, a recombinant adenovirus carrying the gene that encodes murine IL-4 (Ad-mIL-4) was used for...
Search relevance: 71.78 | Views last month: 0 -
Recent work has established that IL-1β plays a central role in the inflammation and connective tissue destruction observed in both rheumatoid arthritis and osteoarthritis. These processes result...
Search relevance: 69.93 | Views last month: 0 -
Indomethacin is a prescription nonsteroidal anti-inflammatory drug (NSAID) available as 75 mg extended-release oral capsules. It works by inhibiting cyclooxygenase enzymes to reduce pain,...
Search relevance: 68.92 | Views last month: 0 -
Staphylococcus aureus is one of the most important pathogens in septic arthritis. To analyse the arthritogenic properties of staphylococcal peptidoglycan (PGN), highly purified PGN from S. aureus...
Search relevance: 66.45 | Views last month: 0 -
Prednisone is a generic corticosteroid medication available as 1 mg oral tablets, used to reduce inflammation and suppress the immune system for conditions like allergies, arthritis, and certain...
Search relevance: 66.35 | Views last month: 0 -
Dexamethasone 1.5 mg tablets are a prescription corticosteroid medication taken orally. As a corticosteroid hormone receptor agonist, it helps reduce inflammation and suppress the immune system,...
Search relevance: 65.72 | Views last month: 0 -
Hydrocortisone is a prescription corticosteroid medication available as oral tablets in 5 mg, 10 mg, and 20 mg strengths. Manufactured by Aurobindo Pharma Limited, it works by reducing...
Search relevance: 65.72 | Views last month: 0 -
Prednisolone Sodium Phosphate is a prescription oral solution, a generic corticosteroid medication used to reduce inflammation and treat conditions like allergies, arthritis, and certain skin...
Search relevance: 65.17 | Views last month: 0 -
YUSIMRY (adalimumab-aqvh) is a prescription biologic drug that blocks tumor necrosis factor, a protein involved in inflammation. It's a monoclonal antibody used to treat autoimmune conditions like...
Search relevance: 64.81 | Views last month: 0 -
Methylprednisolone Sodium Succinate is a corticosteroid medication available as an injectable powder for solution. It helps reduce inflammation, swelling, and immune responses in conditions like...
Search relevance: 64.03 | Views last month: 0
