Found 8 datasets matching "articular-cartilage".
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The extracellular framework and two-thirds of the dry mass of adult articular cartilage are polymeric collagen. Type II collagen is the principal molecular component in mammals, but collagens III,...
Search relevance: 322.41 | Views last month: 0 -
While many proteases in articular cartilage have been described, current studies indicate that members of two families of metalloproteases – MMPs and the ADAMTSs – are responsible for the...
Search relevance: 277.85 | Views last month: 0 -
The reaction patterns of chondrocytes in osteoarthritis can be summarized in five categories: (1) proliferation and cell death (apoptosis); changes in (2) synthetic activity and (3) degradation;...
Search relevance: 265.86 | Views last month: 1 -
Cartilage contains numerous noncollagenous proteins in its extracellular matrix, including proteoglycans. At least 40 such molecules have been identified, differing greatly in structure,...
Search relevance: 192.06 | Views last month: 0 -
Articular cartilage has limited capacity to repair. Defects greater than 3 mm heal with formation of inferior fibrous cartilage. Therefore, many attempts have been made to find the ideal graft for...
Search relevance: 157.66 | Views last month: 0 -
The origin and role of IL-17, a T-cell derived cytokine, in cartilage and bone destruction during rheumatoid arthritis (RA) remain to be clarified. In human ex vivo models, addition of IL-17...
Search relevance: 82.52 | Views last month: 0 -
A possible cause of joint destruction in septic arthritis
Search relevance: 67.21 | Views last month: 0 -
Mast cell (MC) activation in the rheumatoid lesion provides numerous mediators that contribute to inflammatory and degradative processes, especially at sites of cartilage erosion. MC...
Search relevance: 64.97 | Views last month: 0
