Found 17 datasets matching "brain development".
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This dataset includes information on rat dam and pup bodyweights, thyroid hormone concentrations in serum, gene expression in brain, cell counts for cell proliferation in brain. This dataset is...
Search relevance: 125.48 | Views last month: 0 -
The NIH Study of Normal Brain Development is a longitudinal study using anatomical MRI, diffusion tensor imaging (DTI), and MR spectroscopy (MRS) to map pediatric brain development.
Search relevance: 114.75 | Views last month: 29 -
Adequate levels of thyroid hormones (TH) are needed for proper brain development, deficiencies may lead to adverse neurological outcomes in humans and animal models. Environmental chemicals have...
Search relevance: 101.19 | Views last month: 3 -
Background The Rel/NF-κB transcription factors have been shown to regulate apoptosis in different cell types, acting as inducers or blockers in a stimuli- and cell type-dependent...
Search relevance: 90.04 | Views last month: 0 -
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the Drosophila otd...
Search relevance: 84.96 | Views last month: 0 -
Background cDNA-RDA is one of the subtractive cloning techniques used to isolate differentially expressed genes between two complex cDNA populations. In the present study we present a...
Search relevance: 83.77 | Views last month: 0 -
Perchlorate is an environmental contaminant that interferes with iodine uptake via the NIS transporter into the thyroid gland, reducing thyroid hormone (TH) synthesis. As adequate supplies of TH...
Search relevance: 60.38 | Views last month: 1 -
VA's TBI screening and evaluation program will be presented including historical development and progress, operational effectiveness, and research efforts to improve clinical care. Future...
Search relevance: 46.40 | Views last month: 0 -
Data for O'Shaughnessy et al. 2023 - Bypassing the Brain Barriers: Upregulation of Serum miR-495 and miR-543-3p Reflects Thyroid-Mediated Developmental Neurotoxicity in the Rat. This dataset is...
Search relevance: 45.54 | Views last month: 2 -
behavioral measures of learning and memory in adult offspring of rats treated with thyroid hormone synthesis inhibitor, propylthiouracil. Electrophysiological measures of 'memory' in form of...
Search relevance: 45.35 | Views last month: 0 -
Background and Purpose The impact of traumatic brain injury (TBI) on the pathogenesis of Alzheimer disease (AD) is still controversial. The aim of our retrospective autopsy study was to...
Search relevance: 42.85 | Views last month: 3 -
Allergic bronchial asthma (BA) is characterized by chronic airway inflammation, development of airway hyperreactivity and recurrent reversible airway obstruction. T-helper 2 cells and their...
Search relevance: 42.64 | Views last month: 1 -
The Converged Registries Solution (CRS) has been replaced by the Veterans Integrated Registries Platform (VIRP). The information contained in this entry discusses the CRS prior to its...
Search relevance: 41.37 | Views last month: 3 -
Severe thyroid hormone (TH) deprivation during development impairs neurogenesis throughout the brain. The hippocampus also maintains a capacity for neurogenesis throughout life which is reduced in...
Search relevance: 36.88 | Views last month: 1 -
Development of the neurovascular unit (NVU) is a complex, multistage process that requires orchestrated cell signaling mechanisms across several cell types and ultimately results in the formation...
Search relevance: 33.10 | Views last month: 1 -
Thyroid hormones (THs) control normal brain development and function in humans, and identifying environmental thyroid disrupting chemicals has significant public health implications. As such, some...
Search relevance: 30.53 | Views last month: 0