Found 68 datasets matching "cell-interactions".
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Mechanisms whereby T lymphocytes contribute to synovial inflammation in rheumatoid arthritis are poorly understood. Here we review data that indicate an important role for cell contact between...
Search relevance: 196.41 | Views last month: 1 -
The synovial tissue in rheumatoid arthritis (RA) patients is enriched with mature antigen presenting cells (APCs) and many T lymphocytes. Interactions between APCs and T cells are essential for...
Search relevance: 157.15 | Views last month: 0 -
The intricate interactions that regulate relationships between endogenous tissue cells and infiltrating immune cells in the rheumatic joint, particularly in rheumatoid arthritis (RA), were the...
Search relevance: 152.51 | Views last month: 0 -
Leukocyte ingress into the synovium is a key process in the pathogenesis of rheumatoid arthritis and other inflammatory conditions. In this review, the role of endothelial cells in leukocyte...
Search relevance: 108.22 | Views last month: 0 -
In rheumatoid arthritis, T cells and B cells participate in the immune responses evolving in the synovial lesions. Interaction between T cells and B cells is probably antigen specific because...
Search relevance: 105.08 | Views last month: 0 -
The lung is the product of a set of complex developmental interactions between two distinct tissues, the endodermally derived epithelium and the mesoderm. Each tissue contributes to lung...
Search relevance: 53.89 | Views last month: 0 -
Chemical toxicity can arise from disruption of specific biomolecular functions or through more generalized cell stress and cytotoxicity-mediated processes. Here, concentration-dependent responses...
Search relevance: 53.31 | Views last month: 3 -
Background The metalloprotease-disintegrin family, or ADAM, proteins, are implicated in cell-cell interactions, cell fusion, and cell signaling, and are widely distributed among metazoan...
Search relevance: 50.73 | Views last month: 0 -
Cell-scaffold contact measurements are derived from pairs of co-registered volumetric fluorescent confocal laser scanning microscopy (CLSM) images (z-stacks) of stained cells and spun coat, large...
Search relevance: 48.92 | Views last month: 0 -
Fibroblast-like cells in the synovial lining (type B lining cells), stroma and pannus tissue are targeted by many signals, such as the following: ligands binding to cell surface receptors; lipid...
Search relevance: 47.70 | Views last month: 1 -
Background Protein-protein interactions have decisive roles in almost all aspects of the structural and functional organization of cells. But in spite of the increasing amount of...
Search relevance: 46.05 | Views last month: 0 -
Background Modulation of the expression of retinoic acid receptors (RAR) α and γ in adult rat prostate by testosterone (T) suggests that RAR signaling events might mediate some of the...
Search relevance: 45.77 | Views last month: 0 -
Background Epidermal homeostasis involves the monitoring of continuous proliferative and differentiative processes as keratinocytes migrate from the basal layer to the skin surface....
Search relevance: 45.44 | Views last month: 1 -
<p>Develop new cell and blanket technologies and manufacturing processes that reduce overall array costs</p><p>•Cells: develop new cell technology comparable to SOA with reduced cost at...
Search relevance: 45.41 | Views last month: 2 -
There is mounting evidence indicating that the synovial fibroblast is a direct effector of tissue injury and matrix remodeling in inflammatory synovitis. Through the elaboration of effector...
Search relevance: 45.02 | Views last month: 0 -
Background Studies examining herpesvirus-herpesvirus (cytomegalovirus (CMV)-Epstein-Barr virus (EBV)) interactions are limited, and many of the studies have been clinical observations...
Search relevance: 44.65 | Views last month: 0 -
Background The relationship between cell shape, proliferation, and extracellular matrix (ECM) production, important aspects of cell behavior, is examined in a little-studied cell type,...
Search relevance: 44.34 | Views last month: 0 -
Background The tumor suppressor gene PTEN has been found mutated in many types of advanced tumors. When introduced into tumor cells that lack the wild-type allele of the gene, exogenous...
Search relevance: 43.78 | Views last month: 0 -
The data are for a combination of static and dynamic scattering techniques that show there are measurable direct and indirect interactions between soft lipid vesicles in concentrated solutions....
Search relevance: 43.46 | Views last month: 0 -
Acute chest syndrome (ACS) of sickle cell disease (SCD) is characterized pathologically by vaso-occlusive processes that result from abnormal interactions between sickle red blood cells (RBCs),...
Search relevance: 42.87 | Views last month: 2