Found 50 datasets matching "differential expression of genes".
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The aim of this study was to explore the molecular profile of proliferating rheumatoid arthritis synovial fibroblasts (RA-SF). Total RNA was extracted from two cultures of RA-SF (low-density [LD]...
Search relevance: 96.16 | Views last month: 0 -
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques...
Search relevance: 94.64 | Views last month: 3 -
Background: Rat Nb2-11C lymphoma cells are dependent on prolactin for proliferation and are widely used to study prolactin signaling pathways. To investigate the role of this hormone in...
Search relevance: 90.32 | Views last month: 0 -
Background Homeobox genes of the orthodenticle (otd)/Otx family have conserved roles in the embryogenesis of head and brain. Gene replacement experiments show that the Drosophila otd...
Search relevance: 90.00 | Views last month: 0 -
A cell-culture model was used to establish a profile of gene expression during the effector phase of ceramide-mediated cell death. Of the 239 genes that met the criteria for differential...
Search relevance: 87.10 | Views last month: 0 -
Our aim was to identify specifically expressed genes using RNA arbitrarily primed (RAP)-polymerase chain reaction (PCR) for differential display in patients with rheumatoid arthritis (RA). In RA,...
Search relevance: 85.54 | Views last month: 0 -
Deep sequencing technologies were used to construct the first adult female Culicoides sonorensis reference transcriptome. Genetic and genomic tools for Culicoides biting midges are lacking,...
Search relevance: 85.19 | Views last month: 1 -
The data set contains paired-end, 100 nucleotide long RNA sequencing reads for each sample. Raw sequencing reads ranged from 18-30million reads per sample. Quality trimmed reads were mapped to the...
Search relevance: 84.81 | Views last month: 0 -
Background Inhalation of Ascaris suum antigen by allergic monkeys causes an immediate bronchoconstriction and delayed allergic reaction, including a pulmonary inflammatory infiltrate. To...
Search relevance: 84.17 | Views last month: 0 -
Background The development and activation of CD4+ helper T cell (Th) subsets with distinct patterns of unbalanced production of cytokines play an important part in infectious, allergic...
Search relevance: 83.05 | Views last month: 1 -
We address a key baseline question of whether gene expression changes are induced by the orbital environment, and then we ask whether undifferentiated cells, cells presumably lacking the typical...
Search relevance: 82.63 | Views last month: 0 -
Background: Homeotic genes are key developmental regulators that are highly conserved throughout evolution. Their encoded homeoproteins function as transcription factors to control a...
Search relevance: 79.90 | Views last month: 0 -
Background Depending on their larval environment, female honeybees develop into either queens or workers. As in other polyphenisms, this developmental switch depends not on genomic...
Search relevance: 78.79 | Views last month: 3 -
Background Retinoids are very potent inducers of cellular differentiation and apoptosis, and are efficient anti-tumoral agents. Synthetic retinoids are designed to restrict their...
Search relevance: 78.39 | Views last month: 0 -
Intraspecific variation in pathogen shedding impacts disease transmission dynamics; therefore, understanding the host factors associated with individual variation in pathogen shedding is key to...
Search relevance: 78.00 | Views last month: 0 -
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to replicate those...
Search relevance: 77.72 | Views last month: 0 -
Background The gene expression pattern in tumor cells differs from that in corresponding normal cells. In order to identify differentially expressed genes in colorectal tumors and normal...
Search relevance: 76.64 | Views last month: 1 -
Previous spaceflight experiments using Bacillus subtilis have reported altered transcriptome profiles during spaceflight compared to matching ground samples. This study tried to replicate those...
Search relevance: 76.00 | Views last month: 0 -
Data include assessment of pro-inflammatory cytokines, epithelial integrity, bulk RNA sequencing, and gene expression changes in human airway epithelial cells exposed to burn pit smoke...
Search relevance: 75.48 | Views last month: 0 -
Astronauts have been previously shown to exhibit decreased salivary lysozyme and increased dental calculus and gingival inflammation in response to space flight host factors that could contribute...
Search relevance: 74.90 | Views last month: 0
