Found 23 datasets matching "dose-response-study".
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Background: The aim of this prospective study was to assess whether the presence of septic shock could influence the dose response to inhaled nitric oxide (NO) in NO-responding patients...
Search relevance: 213.44 | Views last month: 0 -
These datasets contain information used in support of tables, figures and conclusions made in four manuscripts related to EPA methods developed for the dose-response analysis of epidemiological...
Search relevance: 66.00 | Views last month: 1 -
This dataset contains model code and supporting analysis files necessary to evaluate the impact of variability in human hepatic scaling factors. Variation in scaling factor values impacts...
Search relevance: 63.73 | Views last month: 0 -
Physical and serum chemistry effects in mice due to a single oral dose of ten microcystin congeners at a variety of dose levels to determine health effects and a no observable effect level. This...
Search relevance: 59.58 | Views last month: 0 -
Introduction The aim of the study was to assess the prognostic importance of basal cortisol concentrations and cortisol response to corticotropin, and to determine the effects of...
Search relevance: 59.56 | Views last month: 0 -
se of archival resources has been limited to date by inconsistent methods for genomic profiling of degraded RNA from formalin-fixed paraffin-embedded (FFPE) samples. RNA-seq offers a novel way to...
Search relevance: 59.09 | Views last month: 1 -
Background Manipulation of the uterine epithelium utilising standard dose exogenous oestrogen (E2) and progesterone (P4) has been shown to achieve a mature secretory morphological...
Search relevance: 56.86 | Views last month: 5 -
Background Although much is known about the regulation of osteoclast (OC) formation and activity, little is known about OC senescence. In particular, the fate of of OC seen after...
Search relevance: 56.71 | Views last month: 0 -
Purpose The present study aimed at evaluating the efficacy of Raltitrexed, a specific thymidilate synthase inhibitor, in patients with advanced colorectal cancer (ACC) in relapse (>8...
Search relevance: 50.55 | Views last month: 0 -
Background The standard of care for HCV Hepatitis is the combination of interferon (IFN) plus Ribavirin. In HIV patients the use of this combination therapy may induce drug interactions,...
Search relevance: 49.53 | Views last month: 0 -
This study continues our investigations into the effects of lampricides on mussels by extending research into potential effects on behavioral and reproductive endpoints on the mussel plain...
Search relevance: 47.24 | Views last month: 0 -
This study continues our investigations into the effects of lampricides on mussels by extending research into potential effects on behavioral and reproductive endpoints on the plain pocketbook...
Search relevance: 46.02 | Views last month: 0 -
This data set is comprised of results associated with a multi-stage experimental study to determine the effects of paralytic shellfish toxin ingestion by Common Murres (Uria aalge) conducted in...
Search relevance: 45.34 | Views last month: 0 -
Background The present study was designed to analyze the chronic renal response to omapatrilat, a new vasopeptidase inhibitor, in spontaneously hypertensive rats (SHR). To that end, the...
Search relevance: 43.90 | Views last month: 0 -
Background Helicobacter pylori is the main risk factor for the development of non-cardia gastric cancer. Increased proliferation of the gastric mucosa is a feature of H. pylori...
Search relevance: 42.10 | Views last month: 0 -
Exposure of the airways to cigarette smoke (CS) is the primary risk factor for developing several lung diseases such as Chronic Obstructive Pulmonary Disease (COPD). CS consists of a complex...
Search relevance: 40.29 | Views last month: 3 -
Background The relationship between breast cancer and organochlorine exposure is controversial and complex. As estrogen receptor positive and negative breast cancer may represent...
Search relevance: 40.16 | Views last month: 1 -
Interleukin-11 (IL-11) is a pleiotropic cytokine that regulates the growth and development of hematopoietic stem cells and decreases the proinflammatory mediators of cytokine and nitric oxide...
Search relevance: 38.59 | Views last month: 1 -
Background The Rel/NF-κB transcription factors have been shown to regulate apoptosis in different cell types, acting as inducers or blockers in a stimuli- and cell type-dependent...
Search relevance: 38.58 | Views last month: 0 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 32.64 | Views last month: 1
