Found 17 datasets matching "drug-toxicity".
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A listing of each accidental death associated with drug overdose in Connecticut from 2012 to 2024. A "Y" value under the different substance columns indicates that particular substance was...
Search relevance: 49.84 | Views last month: 1 -
XURIDEN is a prescription drug containing uridine triacetate, available as oral granules (2g per packet). Manufactured by BTG International Inc, it's a pyrimidine analog used in medical...
Search relevance: 46.20 | Views last month: 0 -
Leucovorin Calcium is an injectable prescription drug, a folate analog, used to reduce toxicity from certain chemotherapy medications. It comes as a lyophilized powder for solution, administered...
Search relevance: 46.00 | Views last month: 0 -
Urine samples were derived from a variety of archived industry-led studies, outlined in the dataset. The purpose was to measure a targeted set of miRNA targets that were represented in the Thermo...
Search relevance: 41.66 | Views last month: 0 -
Introduction Acetaminophen toxicity, which can lead to hepatotoxicity, is a burden on our health care system and contributes significantly to intensive care unit admissions and cost of...
Search relevance: 39.86 | Views last month: 5 -
Background Cadmium poisoning in the environment has assumed an alarming problem in recent years. Effective antimutagenic agents which can reverse or combat cadmium induced genotoxicity...
Search relevance: 39.41 | Views last month: 0 -
Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders. Although as many as 20% of treated...
Search relevance: 39.39 | Views last month: 2 -
Acetaminophen overdose is common and can result from deliberate/nonstaggered or accidental/staggered ingestion. Patients presenting within 24 h of an acetaminophen overdose can safely be managed...
Search relevance: 38.53 | Views last month: 0 -
The risks and benefits of stopping antiretroviral therapy in patients admitted to the ICU are largely unmeasured. In many cases therapy has to be stopped, as parenteral preparations are...
Search relevance: 38.44 | Views last month: 0 -
Background Chemotherapy is important in the systematic treatment of breast cancer. To enhance the response of tumours to chemotherapy, attention has been focused on agents to reverse...
Search relevance: 37.92 | Views last month: 0 -
To determine nephron specificity of microRNA expression that may be associated as toxicity biomarker seen in the urine, laser-capture microdissection (LCM) was performed on the 4 major segment of...
Search relevance: 37.49 | Views last month: 0 -
Abstract CI-994 (acetyldinaline) is an investigational anticancer drug currently in clinical trials. In preclinical safety studies in rats and dogs, CI-994 resulted in significant...
Search relevance: 36.52 | Views last month: 0 -
Tamoxifen, a potent anticancer agent known to interrupt the enhanced estrogen activity of malignant mammary gland cells, was recently approved by the Food and Drug Administration (FDA) for the...
Search relevance: 36.32 | Views last month: 0 -
Background Nicotine is a psychoactive drug presenting a diverse array of biological activities, some positive, such as enhancement of cognitive performances, others negative, such as...
Search relevance: 34.31 | Views last month: 0 -
Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a simple AOP network...
Search relevance: 33.39 | Views last month: 0 -
Background The standard of care for HCV Hepatitis is the combination of interferon (IFN) plus Ribavirin. In HIV patients the use of this combination therapy may induce drug interactions,...
Search relevance: 31.81 | Views last month: 0 -
The database provides information on prescribed amounts, levels detected in aquatic environments, chemical structure, molecular weight, octanol-water partition coefficients, water solubility,...
Search relevance: 20.34 | Views last month: 1
