Found 18 datasets matching "endocrine disruptor".
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This paper presents data from studies performed to satisfy test orders from the US EPA’s Endocrine Disruptor Screening Program. Data Evaluation Records were used to collate the control variability...
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These data are from two studies conducted to evaluate the performance of the draft Larval Amphibian Growth and Development Assay for incorporation into the U.S. EPA's Endocrine Disruptor Screening...
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Mercury is a globally distributed pollutant that threatens human and ecosystem health. Even protected areas, such as national parks, are subjected to mercury contamination because it is delivered...
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In response to various legislative mandates the United States Environmental Protection Agency (USEPA) formed its Endocrine Disruptor Screening Program (EDSP), which in turn, implemented a tiered...
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Evaluation of multigenerational effects of 2-ethylhexyl 4-hydroxybenzoate in Japanese medaka Abstract The Japanese medaka (Oryzias latipes) extended one-generation reproduction test (MEOGRT)...
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Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 58.78 | Views last month: 1 -
This dataset provides measured in vitro intrinsic clearance rates for 54 chemicals tested using isolated hepatocytes from humans, rats, and rainbow trout. The test chemicals were selected to...
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A diverse data set of 1667 chemicals with AR experimental activity were provided by the U.S. EPA from the oxicity Forecaster (ToxCast) program which generates data using in vitro high-throughput...
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In the present study, features of gonad metabolite profiles associated with TO in largemouth bass (LMB, Micropterus salmoides) from an impoundment in Georgia (USA) were determined using...
Search relevance: 55.73 | Views last month: 1 -
Data support each of the figures in Boyes et al., Moderate Perinatal Thyroid Hormone Insufficiency Alters Visual System Function in Adult Rats (to be submitted for publication). This dataset is...
Search relevance: 53.39 | Views last month: 0 -
Five chemicals [2-ethylhexyl 4-hydroxybenzoate (2-EHHB), 4-nonylphenol-branched (4-NP), 4-tert-octylphenol (4-OP), benzyl butyl phthalate (BBP) and dibutyl phthalate (DBP) were subjected to a...
Search relevance: 53.10 | Views last month: 1 -
Dataset for the publication "Expanded High-Throughput Screening and Chemotype-Enrichment Analysis of the Phase II:e1k ToxCast Library for Human Sodium-Iodide Symporter (NIS)...
Search relevance: 52.20 | Views last month: 0 -
A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC) were examined for their ability to...
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This high-throughput method will be useful in rapid evaluation of chemicals for nuclear receptor activity for multiple species of interest. The modular design of the assay also permits ready...
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This excel file contains 7 tabs, each tabs contains the data for one specific figure in the paper. Description of the data and column names is also provided in each tab. This dataset is...
Search relevance: 50.66 | Views last month: 1 -
All tables, plus the data for generating figures presented in the manuscript "High-Throughput Screening and Chemotype-Enrichment Analysis of ToxCast Phase II Chemicals Evaluated for Human...
Search relevance: 49.28 | Views last month: 2 -
Final Data SeqAPASS v3.0.zip contains datasets from Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) tool versions 3.0 for all 497 proteins evaluated using Level 1 (primary...
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Biological indicators including morphometric (length, weight), age, sex and health indicators including organismal (health assessment index, condition factor), organ (hepatosomatic index,...
Search relevance: 39.54 | Views last month: 0