Found 13 datasets matching "epidermal-growth-factor".
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Background Leucine-rich repeats are one of the more common modules found in proteins. The leucine-rich repeat consensus motif is LxxLxLxxNxLxxLxxLxxLxx- where the first 11–12 residues...
Search relevance: 284.55 | Views last month: 0 -
Healthy individuals have few goblet cells in their airways, but in patients with hypersecretory diseases goblet-cell upregulation results in mucus hypersecretion, airway plugging, and death....
Search relevance: 220.93 | Views last month: 0 -
Background Modulation of the expression of retinoic acid receptors (RAR) α and γ in adult rat prostate by testosterone (T) suggests that RAR signaling events might mediate some of the...
Search relevance: 174.49 | Views last month: 0 -
Chemical patent from PubChem database. Patent Number: AT-E399541-T1. Title: Method of Treatment Using Chemical Compounds. Filing Date: 2014-06-26. Inventors: Patel, Amit, Jones, Michael. Abstract:...
Search relevance: 118.74 | Views last month: 0 -
The matricellular protein thrombospondin 2 (TSP2) regulates a variety of cell–matrix interactions. A prominent feature of TSP2-null mice is increased microvascular density, particularly in...
Search relevance: 95.91 | Views last month: 0 -
Growth factors mediate tissue interactions and regulate a variety of cellular functions that are critical for normal lung development and homeostasis. Besides their involvement in lung pattern...
Search relevance: 94.05 | Views last month: 0 -
Vectibix (panitumumab) is a prescription monoclonal antibody made by Amgen that targets epidermal growth factor receptors to help treat certain cancers, like metastatic colorectal cancer. It's...
Search relevance: 89.68 | Views last month: 0 -
Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental factors. ...
Search relevance: 86.42 | Views last month: 0 -
Background The membrane-bound cell-surface precursor and soluble forms of heparin-binding epidermal growth factor-like growth factor (HB-EGF) contribute to many cellular developmental...
Search relevance: 74.97 | Views last month: 0 -
Epithelial-mesenchymal interactions drive embryonic fusion events during development and upon perturbation can result in birth defects. Cleft palate and neural tube defects can result from genetic...
Search relevance: 74.45 | Views last month: 0 -
Background In this study, we investigated the mechanism(s) by which delta opioids induce their potent activation of extracellular signal-regulated protein kinases (ERKs) in different...
Search relevance: 65.01 | Views last month: 0 -
Background: Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery,...
Search relevance: 62.73 | Views last month: 0 -
Cleft palate (CP) is a common birth defect, occurring in an estimated 1 in 1000 births worldwide. The secondary palate is formed by paired palatal shelves that grow toward each other, appose,...
Search relevance: 50.43 | Views last month: 1
