• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Nonsteroidal anti-inflammatory drugs (NSAIDs) belong to the most frequently used drugs. The discovery of an inducible isoform of cyclo-oxygenase (COX-2) has led to an intensive worldwide search...

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• Organization: State of Connecticut
• Updated: 2023-06-30

Data on drinking water in Connecticut. Drinking water is a potentially significant route of exposure to contaminants. Today’s regulatory programs are designed to monitor public drinking water...

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• Organization: National Aeronautics and Space Administration
• Updated: 2025-08-21

Data were generated as part of a NASA-funded study (Turek F (PI) et al. Effects of Spaceflight on Gastrointestinal Microbiota in Mice: Mechanisms and Impact on Multi-System. NASA NRA: NRA...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Mefloquine is a clinically important antimalaria drug, which is often not well tolerated. We critically reviewed 516 published case reports of mefloquine adverse effects, to...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Food allergies are generally associated with gastrointestinal upset, but in many patients systemic reactions occur. However, the systemic effects of food allergies are poorly...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Raised levels of both triglycerides and fibrinogen, each of which are reduced by bezafibrate, may contribute to lower extremity arterial disease (LEAD). This condition is...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background Sulfasalazine is a widely used anti-inflammatory agent in the treatment of inflammatory bowel disease and several rheumatological disorders. Although as many as 20% of treated...

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• Organization: National Oceanic and Atmospheric Administration, Department of Commerce
• Updated: 2019-05-15T00:00:00.000+00:00

Sustainable culture of sablefish (Anoplopoma fimbria) is an active research area at NWFSC, with a primary objective of rearing a human food source under healthy, economic, and sustainable...

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• Organization: U.S. Department of Health & Human Services
• Updated: 2025-09-06

Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific...

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