Found 631 datasets matching "gene expression".
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Background Rapid, robust and reversible induction of transgene expression would significantly facilitate cancer gene therapy as well as allow the in vivo functional study of newly...
Search relevance: 208.41 | Views last month: 1 -
Background Poly purine.pyrimidine sequences have the potential to adopt intramolecular triplex structures and are overrepresented upstream of genes in eukaryotes. These sequences may...
Search relevance: 201.46 | Views last month: 0 -
Background Microarray technologies are emerging as a promising tool for genomic studies. The challenge now is how to analyze the resulting large amounts of data. Clustering techniques...
Search relevance: 198.49 | Views last month: 3 -
Background We propose two different formulations of the Rasch statistical models to the problem of relating gene expression profiles to the phenotypes. One formulation allows us to...
Search relevance: 198.05 | Views last month: 0 -
Heat shock protein gene expression and survival in critical illness
Search relevance: 191.29 | Views last month: 0 -
Background Fracture healing slows with age. While 6-week-old rats regain normal bone biomechanics at 4 weeks after fracture, one-year-old rats require more than 26 weeks. The possible...
Search relevance: 189.94 | Views last month: 0 -
Background We performed a statistical analysis of a previously published set of gene expression microarray data from six different brain regions in two mouse strains. In the previous...
Search relevance: 189.72 | Views last month: 0 -
A heuristically modified version of fuzzy k-means clustering has been used to identify overlapping clusters of yeast genes based on published gene-expression data following the response of yeast...
Search relevance: 188.29 | Views last month: 0 -
Respiratory syncytial virus (RSV) and pneumonia virus of mice (PVM) are viruses of the family Paramyxoviridae, subfamily pneumovirus, which cause clinically important respiratory infections in...
Search relevance: 186.34 | Views last month: 0 -
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is DLG5, a member of the...
Search relevance: 183.58 | Views last month: 0 -
Background Retinoids are very potent inducers of cellular differentiation and apoptosis, and are efficient anti-tumoral agents. Synthetic retinoids are designed to restrict their...
Search relevance: 178.19 | Views last month: 0 -
Background: Over the past five years, interest in and use of DNA array technology has increased dramatically, and there has been a surge in demand for different types of arrays. Although...
Search relevance: 177.40 | Views last month: 0 -
A number of brominated flame retardants (BFRs) have been reported to interfere with the thyroid signaling pathway and cause oxidative stress in birds, yet the underlying shifts in gene expression...
Search relevance: 175.27 | Views last month: 0 -
Background Tetracycline-regulated systems have been used to control the expression of heterologous genes in such diverse organisms as yeast, plants, flies and mice. Adaptation of this...
Search relevance: 173.98 | Views last month: 0 -
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however, hampered efforts to...
Search relevance: 173.43 | Views last month: 1 -
Background Drug resistance in breast cancer is a major obstacle to successful chemotherapy. In this study we used cDNA microarray technology to examine gene expression profiles obtained...
Search relevance: 169.82 | Views last month: 6 -
Background Proximal chromosome 15q is implicated in neurodevelopmental disorders including Prader-Willi and Angelman syndromes, autistic disorder and developmental abnormalities...
Search relevance: 169.65 | Views last month: 3 -
Background Microarray experiments offer a potent solution to the problem of making and comparing large numbers of gene expression measurements either in different cell types or in the...
Search relevance: 169.57 | Views last month: 0 -
Background Gene expression is affected by population density. Cell density is a potent negative regulator of cell cycle time during exponential growth. Here, we asked whether SV40 large...
Search relevance: 168.61 | Views last month: 0 -
Background Versatile transgenic manipulation of skeletal muscle requires knowledge of the expression profiles of diverse promoter/enhancer elements in the transcriptionally specialized...
Search relevance: 168.47 | Views last month: 1
