Found 18 datasets matching "gene-deletion".
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Background Mutations in the fibrillin -1 gene (FBN1) cause Marfan syndrome (MFS), an autosomal dominant multi-system connective tissue disorder. The 200 different mutations reported in...
Search relevance: 119.22 | Views last month: 0 -
Background Although all patients undergoing total joint arthroplasty are subjected to similar risk factors that predispose to thromboembolism, only a subset of patients develop this...
Search relevance: 72.58 | Views last month: 0 -
This invention provides a flower organ-specific promoter enabling genetic engineering manipulations of pistil or lodicule. It further provides a novel chitinase expressed specifically in flower...
Search relevance: 61.66 | Views last month: 0 -
Background Many eukaryotes, including plants and fungi make spores that resist severe environmental stress. The micro-organism Dictyostelium contains a single phospholipase C gene (PLC);...
Search relevance: 59.65 | Views last month: 0 -
Background The acetamidase of Mycobacterium smegmatis is a highly inducible enzyme. Expression of this enzyme is increased 100-fold when the substrate acetamide is present. The...
Search relevance: 59.01 | Views last month: 0 -
Background The presynaptic protein α-synuclein is involved in a range of neurodegenerative diseases. Here we analyze potential compensatory mechanisms in α-synuclein null mutant mice....
Search relevance: 55.65 | Views last month: 1 -
Background A breakthrough in the understanding of centriole assembly was provided by the characterization of the UNI3 gene in Chlamydomonas. Deletion of this gene, found to encode a...
Search relevance: 55.33 | Views last month: 0 -
Water buffalo (Bubalus bubalis L.) is an important livestock species worldwide. Like many other livestock species, water buffalo lacks high quality and continuous reference genome assembly,...
Search relevance: 55.30 | Views last month: 0 -
Background Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used...
Search relevance: 55.23 | Views last month: 0 -
Background Currently molecular diagnostic laboratories focus only on the identification of large deletion and duplication mutations (spanning one exon or more) for Duchenne Muscular...
Search relevance: 54.03 | Views last month: 0 -
Genetic fingerprinting of 184 Aspergillus from Ethiopia isolated in 2015 from peanut seeds, raw data
Genetic fingerprinting of 184 Aspergillus section Flavi isolates from Ethiopia screened with 24 Insertion/Deletion markers located within the aflatoxin-biosynthesis gene cluster. Each file name...
Search relevance: 53.41 | Views last month: 0 -
Background SP100 is a nuclear protein that displays a number of alternative splice variants. In Old World monkeys, apes and humans one of these variants is extended by a retroprocessed...
Search relevance: 49.97 | Views last month: 1 -
Background Down syndrome is the most frequent genetic disorder in humans. Rare cases involving partial trisomy of chromosome 21 allowed a small chromosomal region common to all carriers,...
Search relevance: 44.66 | Views last month: 0 -
Low RNA yield and quality limit use of formalin-fixed paraffin-embedded (FFPE) tissue samples for genomic analyses. In this study, we evaluated methods to demodify RNA highly fragmented and...
Search relevance: 43.42 | Views last month: 0 -
Background Exported proteases are commonly associated with virulence in bacterial pathogens, yet there is a paucity of information regarding their role in Mycobacterium tuberculosis....
Search relevance: 39.26 | Views last month: 0 -
Background Some origins in eukaryotic chromosomes fire more frequently than others. In the fission yeast, Schizosaccharomyces pombe, the relative firing frequencies of the three origins...
Search relevance: 38.92 | Views last month: 1 -
Background Living cells constantly sense and adapt to redox shifts by the induction of genes whose products act to maintain the cellular redox environment. In the eukaryote Saccharomyces...
Search relevance: 32.75 | Views last month: 0 -
Data are the individual group values for oral and cloacal virus shedding and antibody titers for reach treatment group from: Mo et al., The pathogenicity and transmission of live bird market H2N2...
Search relevance: 23.84 | Views last month: 0
