Found 25 datasets matching "gene-discovery".
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Novel vectors are described that incorporate, inter alia, a novel 3' gene trap cassette which can be used to efficiently trap and identify previously unknown cellular genes. Vectors incorporating...
Search relevance: 149.65 | Views last month: 1 -
Background The planctomycetes comprise a distinct group of the domain Bacteria, forming a separate division by phylogenetic analysis. The organization of their cells into...
Search relevance: 119.32 | Views last month: 0 -
The Nucleotide database is a collection of sequences from several sources, including GenBank, RefSeq, TPA and PDB. Genome, gene and transcript sequence data provide the foundation for biomedical...
Search relevance: 46.97 | Views last month: 0 -
Background: Sodium bicarbonate cotransporter (NBC) genes encode proteins that execute coupled Na+ and HCO3- transport across epithelial cell membranes. We report the discovery,...
Search relevance: 41.56 | Views last month: 0 -
To further development of our gene expression approach to biodosimetry we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to...
Search relevance: 41.11 | Views last month: 1 -
To further development of our gene expression approach to biodosimetry we have employed whole genome microarray expression profiling as a discovery platform to identify genes with the potential to...
Search relevance: 40.44 | Views last month: 0 -
Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem in most developed countries....
Search relevance: 39.78 | Views last month: 1 -
Space travel presents unlimited opportunities for exploration and discovery, but requires a more complete understanding of the immunological consequences of long-term exposure to the conditions of...
Search relevance: 38.09 | Views last month: 0 -
Background The honeybee (Apis mellifera) has been used with great success in a variety of behavioral studies. The lack of genomic tools in this species has, however, hampered efforts to...
Search relevance: 38.08 | Views last month: 1 -
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of...
Search relevance: 36.69 | Views last month: 0 -
Microgravity as well as chronic muscle disuse are two causes of low back pain originated at least in part from paraspinal muscle deconditioning. At present no study investigated the complexity of...
Search relevance: 36.26 | Views last month: 0 -
Clostridium thermocellum is a thermophilic bacterium recognized for its natural ability to effectively deconstruct cellulosic biomass. While there is a large body of studies on the genetic...
Search relevance: 35.98 | Views last month: 0 -
Background Sites in DNA that bind regulatory proteins can be detected computationally in various ways. Pattern discovery methods analyze collections of genes suspected to be co-regulated...
Search relevance: 35.29 | Views last month: 0 -
Background The EST database provides a rich resource for gene discovery and in silico expression analysis. We report a novel computational approach to identify co-expressed genes using...
Search relevance: 34.35 | Views last month: 0 -
Background The first two steps in the capping of cellular mRNAs are catalyzed by the enzymes RNA triphosphatase and RNA guanylyltransferase. Although structural and mechanistic...
Search relevance: 34.30 | Views last month: 0 -
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling. Thus identification and...
Search relevance: 33.41 | Views last month: 0 -
Bystander mechanisms that originate in the areas surrounding a tissue damage presumably play an important role participating in wound healing and tissue remodeling. Thus identification and...
Search relevance: 33.41 | Views last month: 0 -
Boxwood plants are affected by many different diseases caused by fungi. Some boxwood diseases are deadly and quickly kill the infected plants, but with others, the plant can survive and even...
Search relevance: 30.30 | Views last month: 1 -
This dataset reports discovery and initial comparative analysis of 88 presumptive microRNA (miRNA) sequences from the stable fly, obtained using high-throughput sequencing of small RNAs. The...
Search relevance: 29.84 | Views last month: 0 -
Background The malarial parasite, Plasmodium falciparum (Pf), is responsible for nearly 2 million deaths worldwide. However, the mechanisms of cellular signaling in the parasite remain...
Search relevance: 28.65 | Views last month: 0