Found 67 datasets matching "genetic-factors".
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Background Women may be at increased risk for venous thromboembolism (VTE) as compared with men. We studied the effects of genetic and biochemical markers of thrombophilia in women, in...
Search relevance: 112.87 | Views last month: 3 -
Pulmonary embolism (PE) is one of the leading causes of in-patient hospital deaths. As a consequence, the identification of hemostatic variables that could identify those at risk would be...
Search relevance: 100.50 | Views last month: 0 -
The causes of rheumatoid arthritis (RA) are largely unknown. However, RA is most probably a multifactorial disease with contributions from genetic and environmental factors. Searches for genes...
Search relevance: 97.36 | Views last month: 0 -
Randomized trials and observational studies, such as case-control studies, are often seen as opposing approaches. However, in many instances results obtained by different designs may complement...
Search relevance: 88.18 | Views last month: 3 -
Background Family history and twins studies suggest an inherited component to ischemic stroke risk. Candidate gene association studies have been performed but have limited capacity to...
Search relevance: 75.20 | Views last month: 0 -
Dead-end sections of drinking water distribution networks are known to be problematic zones in terms of water quality degradation. Extended residence time due to water stagnation leads to rapid...
Search relevance: 68.90 | Views last month: 0 -
The existence of psoriatic arthritis as a distinct clinical entity remains a topic of debate; some authors propose that it is simply the co-occurrence of psoriasis and inflammatory arthritis....
Search relevance: 62.01 | Views last month: 0 -
Asthma and associated phenotypes are complex traits most probably caused by an interaction of multiple disease susceptibility genes and environmental factors. Major achievements have occurred in...
Search relevance: 59.09 | Views last month: 3 -
Chronic obstructive pulmonary disease (COPD) is a significant cause of global morbidity and mortality. Previous studies have shown that COPD aggregates in families, suggesting a genetic...
Search relevance: 54.63 | Views last month: 0 -
Osteoarthritis and osteoporosis are the two most common age-related chronic disorders of articular joints and skeleton, representing a major public health problem in most developed countries....
Search relevance: 54.38 | Views last month: 0 -
Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental factors. ...
Search relevance: 52.81 | Views last month: 0 -
The basis of susceptibility to rheumatoid arthritis (RA) is complex, comprising genetic and environmental susceptibility factors. We have reviewed the available approaches to the investigation of...
Search relevance: 52.62 | Views last month: 1 -
Meat producing animals in agriculture are the result of ongoing genetic selection for desirable characteristics related to growth rates, feed efficiencies, product yield, and quality. Skeletal...
Search relevance: 51.72 | Views last month: 0 -
In sarcoidosis, host genetic factors are discussed as contributing to disease susceptibility and course. Since tumor necrosis factor (TNF)-α is a central mediator of granuloma formation and since...
Search relevance: 50.30 | Views last month: 0 -
Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem in most developed countries....
Search relevance: 50.09 | Views last month: 1 -
Giant cell arteritis (GCA) (temporal arteritis) and polymyalgia rheumatica (PMR) are common, frequently related conditions in people generally over 50 years of age. Most studies have shown an...
Search relevance: 49.44 | Views last month: 0 -
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine models of systemic...
Search relevance: 48.88 | Views last month: 7 -
Background In order to maintain populations as units of reproduction and thus enable anagenetic evolution, genetic factors must exist which prevent continuing reproductive separation or...
Search relevance: 48.36 | Views last month: 0 -
The Southern Resident killer whale (SRKW) population is threatened by a number of identified risk factors including prey availability, contaminants, vessel noise and disturbance, and small...
Search relevance: 47.65 | Views last month: 0 -
Functional connectivity, quantified using landscape genetics, can inform conservation through the identification of factors linking genetic structure to landscape mechanisms. We used breeding...
Search relevance: 47.43 | Views last month: 0
