Found 25 datasets matching "genetic-linkage".
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Background The legume Medicago truncatula has emerged as a model plant for the molecular and genetic dissection of various plant processes involved in rhizobial, mycorrhizal and...
Search relevance: 230.18 | Views last month: 0 -
Genetic linkage maps are valuable tools in evolutionary biology; however, their availability for wild populations is extremely limited. Fundulus heteroclitus (Atlantic killifish) is a...
Search relevance: 211.14 | Views last month: 1 -
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by the production of autoantibodies to a wide range of self-antigens. Recent genome screens have implicated...
Search relevance: 144.27 | Views last month: 0 -
Genome-wide linkage analysis studies in families with systemic lupus erythematosus (SLE) have revealed consistent evidence of linkage to several regions of the genome. In a previous issue of this...
Search relevance: 132.12 | Views last month: 0 -
The basis of susceptibility to rheumatoid arthritis (RA) is complex, comprising genetic and environmental susceptibility factors. We have reviewed the available approaches to the investigation of...
Search relevance: 116.85 | Views last month: 1 -
Background Celiac disease has a strong genetic association with HLA. However, this association only explains approximately half of the sibling risk for celiac disease. Therefore, other...
Search relevance: 107.16 | Views last month: 3 -
Background Cerebrovascular disease is the third leading cause of death in the United States, and about one-fourth of cerebrovascular deaths are attributed to ruptured intracranial...
Search relevance: 99.51 | Views last month: 0 -
Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to examine the linkage...
Search relevance: 67.47 | Views last month: 0 -
Background To learn about the molecular etiology of strabismus, we are studying the genetic basis of 'congenital fibrosis of the extraocular muscles' (CFEOM). These syndromes are...
Search relevance: 60.65 | Views last month: 0 -
Spontaneous premature ovarian failure presents most commonly with secondary amenorrhea. Young women with the disorder are infertile and experience the symptoms and sequelae of estrogen deficiency....
Search relevance: 60.63 | Views last month: 0 -
Systemic sclerosis (SSc) is a multisystem connective tissue disease characterised phenotypically by fibrosis and ischaemic atrophy. Its aetiology is most likely multifactorial. A genetic...
Search relevance: 58.13 | Views last month: 2 -
Systemic lupus erythematosus is the prototype multisystem autoimmune disease. A strong genetic component of susceptibility to the disease is well established. Studies of murine models of systemic...
Search relevance: 56.47 | Views last month: 7 -
MapViewer is a graphical tool for viewing and comparing Gossypium spp. genetic maps. It includes dynamically scrollable maps, correspondence matrices, dot plots, links to details about map...
Search relevance: 54.87 | Views last month: 1 -
Primary ciliary dyskinesia (PCD) is a genetic disorder of abnormal ciliary structure and function that leads to defective mucociliary clearance, resulting in oto-sino-pulmonary disease, and...
Search relevance: 46.38 | Views last month: 0 -
This data set contains 32 million annotated SNPs having an average SNP density of 30 SNPs per kb and 12 non-synonymous SNPs per gene model. These SNPs were identified from a genetically diverse,...
Search relevance: 46.11 | Views last month: 0 -
The American cranberry (Vaccinium macrocarpon Ait.) is a recently domesticated, economically important, fruit crop with limited molecular resources. New genetic resources could accelerate genetic...
Search relevance: 43.67 | Views last month: 1 -
Huanglongbing (HLB) is one of the most destructive citrus diseases in the world. The disease is associated with the presence of a fastidious, phloem-limited α- proteobacterium, 'Candidatus...
Search relevance: 43.22 | Views last month: 0 -
Sweetpotato (Ipomoea batatas) plays a critical role in food security and is the most important root crop worldwide following potatoes and cassava. In the United States (US), it is valued at over...
Search relevance: 39.75 | Views last month: 0 -
Phenotypic Data Two durum × cultivated emmer recombinant inbred line (RIL) populations were evaluated for grain yield components under field conditions in North Dakota, USA. The BP025 population...
Search relevance: 38.24 | Views last month: 0 -
The ascomycete fungus Cryphonectria parasitica is the causal agent of chestnut blight disease. This deadly fungal pathogen was introduced into North America from Asia before the turn of the 20th...
Search relevance: 37.03 | Views last month: 1