Found 43 datasets matching "genetic-polymorphism".
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Background Vitamin D has been shown to exert manifold immunomodulatory effects. Type 1 diabetes mellitus (T1DM) is regarded to be immune-mediated and vitamin D prevents the development...
Search relevance: 143.65 | Views last month: 0 -
The study of genetic polymorphisms has touched every aspect of pulmonary and critical care medicine. We review recent progress made using genetic polymorphisms to define pathophysiology, to...
Search relevance: 124.54 | Views last month: 0 -
Background Single-nucleotide polymorphisms (SNPs) are considered to be useful polymorphic markers for genetic studies of polygenic traits. Single-stranded conformational polymorphism...
Search relevance: 104.59 | Views last month: 0 -
Background The involvement of β2-adrenergic receptor (ADRB2) and β3-adrenergic receptor (ADRB3) in both adipocyte lipolysis and thermogenic activity suggests that polymorphisms in the...
Search relevance: 89.14 | Views last month: 1 -
Acropora cervicornis, A. palmata and Orbicella faveolata are important reef-building coral species in the Florida Reef Tract (FRT). These species have experienced alarming declines throughout the...
Search relevance: 78.70 | Views last month: 0 -
The interleukin-4 (IL-4) signalling cascade has been identified as a pathway potentially important in the development of asthma. Genetic variants within this signalling pathway might contribute to...
Search relevance: 68.00 | Views last month: 0 -
Conversion and fragmentation of wildlife habitat often leads to smaller and isolated populations and can reduce a species’ ability to disperse across the landscape. As a consequence, genetic drift...
Search relevance: 66.13 | Views last month: 0 -
Background The gene encoding apolipoprotein E (APOE) has been proposed as a candidate gene for vascular complications in Type I diabetes. This study aimed to investigate the influence of...
Search relevance: 64.19 | Views last month: 2 -
Background Recent studies of ancestral maize populations indicate that linkage disequilibrium tends to dissipate rapidly, sometimes within 100 bp. We set out to examine the linkage...
Search relevance: 63.18 | Views last month: 0 -
We used genome-wide single nucleotide polymorphism (SNP) data and capture-mark-recapture methods to evaluate the genetic diversity and demography within seven focal sites of the endangered San...
Search relevance: 63.08 | Views last month: 2 -
A genetic analyses of samples from the Chinook salmon (Oncorhynchus tshawytscha) bycatch from the 2007-2013 Bering Sea-Aleutian Island and Gulf of Alaska trawl fisheries for walleye pollock (Gadus...
Search relevance: 62.25 | Views last month: 0 -
Background Although all patients undergoing total joint arthroplasty are subjected to similar risk factors that predispose to thromboembolism, only a subset of patients develop this...
Search relevance: 61.41 | Views last month: 0 -
Osteoporosis (OP) and osteoarthritis (OA), the two most common age-related chronic disorders of articular joints and skeleton, represent a major public health problem in most developed countries....
Search relevance: 60.50 | Views last month: 1 -
Background The autoimmune thyroid diseases (AITDs), such as Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of complex interactions between...
Search relevance: 59.15 | Views last month: 0 -
Background The legume Medicago truncatula has emerged as a model plant for the molecular and genetic dissection of various plant processes involved in rhizobial, mycorrhizal and...
Search relevance: 57.59 | Views last month: 0 -
Genetic samples in the form of a small blood sample were collected from 263 Bell’s vireos (Vireo bellii) in drainages throughout southern and central California, Arizona, southern Nevada, and...
Search relevance: 57.53 | Views last month: 0 -
This data release comprises a dataset that contains sample collection information and microsatellite genotypes, and another dataset that contains single nucleotide polymorphism (SNP) genotypes...
Search relevance: 57.51 | Views last month: 0 -
Background Women may be at increased risk for venous thromboembolism (VTE) as compared with men. We studied the effects of genetic and biochemical markers of thrombophilia in women, in...
Search relevance: 54.72 | Views last month: 3 -
Background Changes in breast density are highly correlated with steroid hormone exposure. Materials and methods In a cross-sectional study of 396...
Search relevance: 51.43 | Views last month: 2 -
Background Breast cancer is hormone related, as are cancers of the endometrium, ovary, and prostate. Several studies have suggested that higher extracellular levels of androgens are...
Search relevance: 51.12 | Views last month: 0
