Found 16 datasets matching "glucocorticoids".
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It is not known to what extent glucocorticoid hormones cause their anti-inflammatory actions and their undesirable side effects by the same or different molecular mechanisms. Glucocorticoids...
Search relevance: 144.50 | Views last month: 0 -
Most anti-inflammatory drugs have been associated with an increased risk of serious upper gastrointestinal complications. Epidemiological studies have estimated the magnitude of the risk for...
Search relevance: 82.08 | Views last month: 0 -
Dorsal third ventricle infusions of the alpha 2 adrenergic receptor antagonist, mianserin- which increases brain concentrations of dopamine, serotonin, and acetylcholine, or the glucocorticoid...
Search relevance: 72.89 | Views last month: 0 -
Glucocorticoids (GCs) are routinely used as anti-inflammatory drugs in the treatment of asthma. They act through binding to glucocorticoid receptor α (GRα), which represses numerous genes encoding...
Search relevance: 64.76 | Views last month: 0 -
Background In most cells glucocorticoid receptors (GR) reside predominately in the cytoplasm. Upon hormone binding, the GR translocates into the nucleus, where the hormone-activated...
Search relevance: 40.43 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a nationwide screen of United States stream water samples. In vitro bioassays...
Search relevance: 38.41 | Views last month: 0 -
Hypothalamic–pituitary–adrenal underactivity has been reported in rheumatoid arthritis (RA). This phenomenon has implications with regard to the pathogenesis and treatment of the disease. The...
Search relevance: 35.24 | Views last month: 0 -
Individuals with psychosocial stress often experience an exaggerated response to air pollutants. Ozone (O3) exposure has been associated with the activation of the neuroendocrine stress-response...
Search relevance: 32.85 | Views last month: 1 -
Decision-making in the intensive care unit is often very difficult. Although we are encouraged to make evidence-based decisions, this may be difficult for a number of reasons. To begin with,...
Search relevance: 31.62 | Views last month: 0 -
Frontiers in Toxicology paper, Differential transcriptomic alterations in nasal versus lung tissue of acrolein-exposed rats, 2023 Alewel DI. This dataset is associated with the following...
Search relevance: 31.10 | Views last month: 0 -
Excel file containing individual data points for all figures and tables in the manuscript.
Search relevance: 30.88 | Views last month: 0 -
In vitro bioactivity concentrations and chemical concentrations of estrogens, androgens, and glucocorticoids from a pilot study of US tapwaters. In vitro bioassays include T47D-Kbluc, MDA-kb2, and...
Search relevance: 30.32 | Views last month: 1 -
This ScienceHub file shows the physiological data associated with the manuscript Adrenal Stress Hormone Regulation of Hepatic Homeostatic Function After an Acute Ozone Exposure in Wistar-Kyoto...
Search relevance: 28.98 | Views last month: 0 -
Rheumatoid arthritis (RA) patients experience a markedly increased frequency of cardiovascular disease. We evaluated cardiovascular risk profiles in 79 RA patients and in 39 age-matched and...
Search relevance: 23.62 | Views last month: 0 -
Disruption of steroidogenesis by environmental chemicals can result in altered hormone levels causing adverse reproductive and developmental effects. A high-throughput assay using H295R human...
Search relevance: 22.37 | Views last month: 0 -
Background Recent reports have raised concerns that postnatal steroids may cause neuro-developmental impairment in preterm infants. This systematic review was performed with the...
Search relevance: 21.51 | Views last month: 3
