Found 12 datasets matching "glycosylation".
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The cystic fibrosis transmembrane conductance regulator (CFTR) has been known for the past 11 years to be a membrane glycoprotein with chloride channel activity. Only recently has the...
Search relevance: 157.66 | Views last month: 1 -
Background The tissue accumulation of protein-bound advanced glycation endproducts (AGE) may be involved in the etiology of diabetic chronic complications, including osteopenia. The aim...
Search relevance: 89.28 | Views last month: 0 -
A method is provided for increasing the specific activity of a type III antifreeze protein when said protein is prepared by expression in a heterologous fungal species of a gene encoding the...
Search relevance: 47.22 | Views last month: 0 -
Background The capsaicin (vanilloid) receptor, VR1, is an agonist-activated ion channel expressed by sensory neurons that serves as a detector of chemical and thermal noxious stimuli. ...
Search relevance: 41.91 | Views last month: 0 -
Both type I and type II diabetes are powerful and independent risk factors for coronary artery disease (CAD), stroke, and peripheral arterial disease. Atherosclerosis accounts for virtually 80% of...
Search relevance: 41.30 | Views last month: 1 -
Background Ca2+-ATPases of endoplasmic reticulum (SERCAs) are responsible for maintenance of the micro- to millimolar Ca2+ ion concentrations within the endoplasmic reticulum (ER) of...
Search relevance: 39.98 | Views last month: 0 -
The neutrophil azurophil granule constituent proteinase 3 (PR3) is the principal antigen for anti-neutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis. The conformation of the...
Search relevance: 36.73 | Views last month: 0 -
Background Secretion of recombinant proteins in yeast can be affected by their improper folding in the endoplasmic reticulum and subsequent elimination of the misfolded molecules via the...
Search relevance: 32.02 | Views last month: 0 -
Background In eukaryotic cells, proteins are translocated across the ER membrane through a continuous ribosome-translocon channel. It is unclear to what extent proteins can fold already...
Search relevance: 29.68 | Views last month: 0 -
This database gives hydrogen-deuterium exchange mass spectrometry (HDX-MS) data from measurements of three purified IgG1 glycoform samples, predominantly G0F, G2F, and SAF, in isolation and in...
Search relevance: 28.66 | Views last month: 5 -
Background: Protein fold recognition using sequence profile searches frequently allows prediction of the structure and biochemical mechanisms of proteins with an important biological...
Search relevance: 28.40 | Views last month: 0 -
Background To maintain organelle integrity, resident proteins must segregate from itinerant cargo during secretory transport. However, Golgi resident enzymes must have intimate access to...
Search relevance: 27.16 | Views last month: 0
