Found 22 datasets matching "human liver".
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Gene array data files compared gene expression profiles in liver samples from young (21-45 years) and old (69+ years) men and women to determine changes in the expression of xenobiotic metabolism...
Search relevance: 163.17 | Views last month: 1 -
Data for "Addicks GC, Rowan-Carroll A, Reardon A, Leingartner K, Williams A, Meier MJ, Moffat I, Carrier R, Lorusso L, Wetmore BA, Yauk C, Atlas E. Per- and Polyfluoroalkyl Substances (PFAS) in...
Search relevance: 124.81 | Views last month: 1 -
Current studies on nontarget analysis and toxicities of PFASs are disconnected, due to the challenges posed by the large numbers (>1,000) and diverse structures of PFASs. The SECC method provides...
Search relevance: 110.77 | Views last month: 0 -
individual values for liver detoxification for each human sample and for each chemical. This dataset is associated with the following publication: Moser, G., and S. Padilla. Esterase...
Search relevance: 63.65 | Views last month: 0 -
Background The search for an optimal experimental model in pharmacology is recently focused on (mini)pigs as they seem not only to be an alternative source of cells and tissues for...
Search relevance: 55.51 | Views last month: 0 -
Background The past three decades have witnessed the rise of Campylobacter enteritis in man from virtual obscurity to notoriety, with present isolation rates superseding those of other...
Search relevance: 54.99 | Views last month: 0 -
Background Nocturnin was originally identified by differential display as a circadian clock regulated gene with high expression at night in photoreceptors of the African clawed frog,...
Search relevance: 50.09 | Views last month: 0 -
Isopeptides (ε-peptides) of lysine, with a given Mw and low polydispersity (10–400 units), were synthesized to study the relationship between their chemical structure and biological effect. The...
Search relevance: 45.49 | Views last month: 1 -
Perfluorononanoic acid (PFNA) is one of the perfluoroalkyl acids found in the environment and in tissues of humans and wildlife. Prenatal exposure to PFNA negatively impacts survival and...
Search relevance: 42.94 | Views last month: 0 -
The US EPA’s ToxCast program is designed to assess chemical perturbations of molecular and cellular endpoints using a variety of high-throughput screening (HTS) assays. However, existing HTS...
Search relevance: 42.03 | Views last month: 0 -
Carbon nanotubes (CNTs) have great potential in industrial, consumer, and mechanical applications, based partly on their unique structural, optical and electronic properties. CNTs are commonly...
Search relevance: 39.90 | Views last month: 0 -
Given the limited knowledge of the biological impact of spaceflight, a multi-omics, systems biology approach was used to investigate NASA’s GeneLab data and astronaut biomedical profiles. These...
Search relevance: 39.17 | Views last month: 0 -
These data are summaries of pro-inflammatory cytokine and insulin resistance serum biomarkers; necrotic liver disease defined by serum keratin 18 (K18) biomarkers. Associations were determined...
Search relevance: 38.51 | Views last month: 0 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 37.84 | Views last month: 6 -
Data was generated at KUMC, not EPA. There is no EPA data that is part of this submission. This dataset is associated with the following publication: Liu, J., J.Y. Cui, Y. Lu, C. Corton, and C....
Search relevance: 37.21 | Views last month: 0 -
Background Familial atrial fibrillation, an autosomal dominant disease, was previously mapped to chromosome 10q22. One of the genes mapped to the 10q22 region is DLG5, a member of the...
Search relevance: 36.29 | Views last month: 0 -
Background Previously, we have demonstrated a marked inhibition of codeine glucuronidation by diclofenac in human liver tissue homogenate. We therefore aimed to investigate whether...
Search relevance: 35.55 | Views last month: 0 -
Background The outgrowth of new vessels – angiogenesis – in the tumour mass is considered to be a limiting factor of tumour growth. To inhibit the matrix lysis that is part of the tumour...
Search relevance: 34.71 | Views last month: 0 -
Background A "physiologically based pharmacokinetic" (PBPK) approach uses a realistic model of the animal to describe the pharmacokinetics. Previous PBPKs have been designed for specific...
Search relevance: 32.94 | Views last month: 1 -
Background Hepatitis C is a serious problem on the Greek island of Crete, where a high prevalence of antibodies against hepatitis C (anti-HCV) has recently been reported. This article...
Search relevance: 30.86 | Views last month: 0
