Found 59 datasets matching "in vitro assays".
-
Files contain summary reports of chemical and Mass Spectrometry raw and analyzed data used as basis for plot generation and text discussions in the Cyclic phenone metabolism manuscript. File...
Search relevance: 185.99 | Views last month: 0 -
The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
Search relevance: 178.43 | Views last month: 0 -
Supplementary data for "A comparative study of biostatistical pipelines for benchmark concentration modeling of in vitro screening assays". This dataset is associated with the following...
Search relevance: 167.77 | Views last month: 0 -
Data for Hopperstad K and Deisenroth C (2023) Development of a bioprinter-based method for incorporating metabolic competence into high-throughput in vitro assays. Front. Toxicol. 5:1196245. doi:...
Search relevance: 160.87 | Views last month: 0 -
Dataset for Jurgelewicz, A. et al, 'Assessing the impact of in vitro xenobiotic metabolism on estrogenic chemical bioactivity in high-throughput profiling assays' published in Toxicology, Vol 517,...
Search relevance: 157.85 | Views last month: 0 -
Supplementary data for "Stephanie A. Eytcheson, Jennifer H. Olker, Katie Paul Friedman, Michael W. Hornung, Sigmund J. Degitz, Assessing utility of thyroid in vitro screening assays through...
Search relevance: 157.05 | Views last month: 1 -
1) % Viability of human reconstructed skin exposed to cerium, silver and titanium nanoparticles; 2) Zeta potential of the nanoparticles in media. This dataset is associated with the following...
Search relevance: 155.25 | Views last month: 1 -
This file contains the data on apoptosis, neurite outgrowth, synaptogenesis and proliferation. This dataset is associated with the following publication: Harrill, J., T. Freudenrich, K. Wallace,...
Search relevance: 115.96 | Views last month: 0 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 74.42 | Views last month: 6 -
A dataset for the manuscript which demonstrates that it is possible to achieve levels of performance equivalent to the full 16 assay ER agonist model against both in vitro and in vivo reference...
Search relevance: 70.03 | Views last month: 0 -
Screening certain environmental chemicals for their ability to interact with endocrine targets, including the androgen receptor (AR), is an important global concern. We previously developed a...
Search relevance: 68.96 | Views last month: 0 -
Data for "Estrogenic Activity of Perfluoro Carboxylic and Sulfonic Acids in Rainbow Trout Estrogen Receptor Binding and Liver Slice Vtg mRNA Expression Assays. Mark A. Tapper, Jeffrey S. Denny,...
Search relevance: 65.64 | Views last month: 0 -
Results of single concentration and concentration response testing of 165 PFAS samples from the USEPA ToxCast chemical library in nine (9) thyroid relevant assays. Chemicals were first screened in...
Search relevance: 65.00 | Views last month: 1 -
Phenones and hydroxy benzophenones are widely used as UV radiation filters, and in the manufacturing of insecticides and pharmaceuticals. Understanding the ability of these chemicals to mimic the...
Search relevance: 63.44 | Views last month: 0 -
This dataset consists of data from in vitro developmental neurotoxicity new approach methodologies (DNT-NAMs). Assays include evaluations of proliferation, apoptosis, viability, neurite outgrowth,...
Search relevance: 60.74 | Views last month: 1 -
A representative group of multicyclic aromatic hydrocarbons (MAHC) which can be further classified as bridged-ring (bridged-MAHC) or fused-ring (fused-MAHC) were examined for their ability to...
Search relevance: 60.22 | Views last month: 0 -
Dataset of medium throughput (96 well plate) in vitro nuclear receptor activation assays for peroxisome proliferator activated receptor alpha (PPARa), PPAR gamma (PPARg), and estrogen receptor...
Search relevance: 59.99 | Views last month: 0 -
This dataset contains the raw data, Area under the curve measurements and EC50 values for effects of 146 compounds (136 unique plus 10 biological replicates) on parameters of network development...
Search relevance: 59.38 | Views last month: 1 -
Background The mos proto-oncogene encodes a cytoplasmic serine/threonine-specific protein kinase with crucial function during meiotic cell division in vertebrates. Based on oncogenic...
Search relevance: 58.27 | Views last month: 0 -
Background Human herpesvirus-8 (HHV-8) is linked to the pathogenesis of Kaposi's sarcoma (KS), and the HHV-8 DNA load in peripheral blood mononuclear cells (PBMC) is associated with the...
Search relevance: 58.17 | Views last month: 0
