Found 36 datasets matching "in vitro toxicity data".
-
Supplemental data for "Schaupp CM, Maloney EM, Mattingly K, Olker JH, Villeneuve DL. Comparison of in silico, in vitro, and in vivo toxicity benchmarks suggests a role for ToxCast data in...
Search relevance: 156.42 | Views last month: 1 -
Three recent IARC Working Groups pioneered inclusion of the US Environmental Protection Agency (EPA) ToxCast program high-throughput screening (HTS) data to supplement other mechanistic evidence....
Search relevance: 129.58 | Views last month: 2 -
Treating Shiga toxin-producing Escherichia coli (STEC) gastrointestinal infections is difficult. The utility of antibiotics for STEC treatment is controversial, since antibiotic resistance among...
Search relevance: 85.70 | Views last month: 0 -
Background: Chemical toxicity testing is being transformed by advances in biology and computer modeling, concerns over animal use and the thousands of environmental chemicals lacking toxicity...
Search relevance: 72.33 | Views last month: 6 -
This data includes metabolite predictions for in vitro inactive chemicals, predictions of those metabolite's estrogen receptor binding activity, in vitro and in silico information regarding parent...
Search relevance: 63.98 | Views last month: 0 -
The US EPA Toxicity Forecasting (ToxCast) project has involved the generation of large amount of high throughput in vitro data (Over 4000 chemicals tested in between 100 and 700 assays). This data...
Search relevance: 63.88 | Views last month: 0 -
In vitro biological activity data from a extracts of a nationwide survey of US streams. This dataset is associated with the following publication: Blackwell, B., G. Ankley, P. Bradley, K. Houck,...
Search relevance: 62.89 | Views last month: 0 -
R-language data files from "Carstens KE, Freudenrich T, Wallace K, Choo S, Carpenter A, Smeltz M, Clifton MS, Henderson WM, Richard AM, Patlewicz G, Wetmore BA, Paul Friedman K, Shafer T....
Search relevance: 61.63 | Views last month: 0 -
Dose response viability data of rat and human intestinal cells exposed to copper oxide nanoparticles (CuO, Cu2O), CuSO4 and CuCl (rat cells only). Assays examining a potential mechanism of...
Search relevance: 59.80 | Views last month: 0 -
Dataset consists of high throughput in vitro bioactivity data and exposure predictions from the U.S. EPA’s Toxicity and Exposure Forecaster (ToxCast and ExpoCast) project. This dataset is...
Search relevance: 59.10 | Views last month: 1 -
This dataset comprises one SigmaPlot 13 file containing measured survival data and survival data predicted from the model coefficients selected by the LASSO procedure. This dataset is associated...
Search relevance: 58.77 | Views last month: 0 -
We use a supervised machine learning strategy to systematically investigate the relative importance of study type, machine learning algorithm, and type of descriptor on predicting in vivo...
Search relevance: 56.18 | Views last month: 0 -
Read-across is a popular data gap filling technique within category and analogue approaches for regulatory purposes. Acceptance of read-across remains an ongoing challenge with several efforts...
Search relevance: 52.96 | Views last month: 0 -
Data accompanying the manuscript titled, "Liquid Application Dosing Alters Air-Liquid-Interface Bronchial Epithelial Culture Physiology and Toxicity Testing Relevant Endpoints" Authors: Nicholas...
Search relevance: 52.39 | Views last month: 0 -
The data used in this analysis was obtained from published literature and available through the high-throughput toxicokinetic (HTTK) R package. The dataset consists of 1486 chemicals that span a...
Search relevance: 51.70 | Views last month: 0 -
The data presented here support the application of the Stemina devTOXqP platform for predictive toxicology and further demonstrate its value in ToxCast as a novel resource that can generate...
Search relevance: 51.06 | Views last month: 0 -
The contents of the chemistry database, presently containing ~ 760,000 substances, are available as public domain data for download. The chemistry content underpinning the Dashboard has been...
Search relevance: 48.60 | Views last month: 6 -
The revised paper dataset includes data shown in the main paper and supplemental file and are derived from Excel files associated with this Science Hub entry. The Word file "Science Hub Record...
Search relevance: 47.36 | Views last month: 0 -
Aggregated Computational Toxicology Online Resource (AcTOR) is EPA's online aggregator of all the public sources of chemical toxicity data. ACToR aggregates data from over 1,000 public sources on...
Search relevance: 47.17 | Views last month: 14 -
Background: Trends in male reproductive health have been reported for increased rates of testicular germ cell tumors, low semen quality, cryptorchidism, and hypospadias, which have been associated...
Search relevance: 46.28 | Views last month: 3
