Found 193 datasets matching "inhibitor".
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Background This work represents an extensive MD simulation / water-dynamics studies on a series of complexes of inhibitors (leupeptin, E-64, E-64-C, ZPACK) and plant cysteine proteases...
Search relevance: 121.68 | Views last month: 0 -
Adverse outcome pathway (AOP) networks potentially provide a basis for predictive approaches to assess the toxicity of chemical mixtures. This study evaluated the utility of a simple AOP network...
Search relevance: 106.13 | Views last month: 0 -
Background Angiotensin converting enzyme inhibitors are routinely prescribed to patients with chronic kidney disease because of their known renoprotective effects. We evaluated the...
Search relevance: 105.48 | Views last month: 0 -
Wetlands are frequently used in the U.S. for treating nitrate in agricultural runoff. However, numerous other biologically active contaminants, such as antibiotics and nitrification inhibitors,...
Search relevance: 94.23 | Views last month: 0 -
A method for the preparation of homogenous microparticles containing a H+, K+-ATP-ase inhibitor using a fluid-bed granulation technique. The microparticles that have a desired size distribution...
Search relevance: 91.22 | Views last month: 0 -
Background Growth inhibition by RPR-130401, a non-peptidomimetic farnesyltransferase inhibitor, was investigated without or with combined exposure to ionizing radiation in three human...
Search relevance: 90.76 | Views last month: 0 -
Secretory leukocyte proteinase inhibitor and elafin are two low-molecular-mass elastase inhibitors that are mainly synthesized locally at mucosal sites. It is thought that their physicochemical...
Search relevance: 87.57 | Views last month: 0 -
Compounds of formula (I), methods for their preparation and their use in the manufacture of neuraminidase inhibitor conjugates. Wherein R represents as carboxylic acid protecting group; P1 and P2...
Search relevance: 81.65 | Views last month: 1 -
Background Inhibitor of Apoptosis (IAP) proteins are key intrinsic regulators of apoptosis induced by a variety of triggers. We isolated the rat Inhibitor of Apoptosis genes 1, 2 and 3...
Search relevance: 80.23 | Views last month: 0 -
The present invention is directed to a novel form of a pyrrolopyridine-2-carboxylic acid amide of formula (I), which is an inhibitor of glycogen phosphorylase, compositions containing it and their...
Search relevance: 78.35 | Views last month: 1 -
Inhibition of the sodium-hydrogen exchanger (NHE) is a powerful experimental tool to inhibit sodium and calcium accumulation within the ischemic myocyte and halt progression of cell ischemia to...
Search relevance: 75.55 | Views last month: 0 -
The main manifestation of systemic sclerosis (SSc) is the overproduction of extracellular matrix, predominantly type I collagen. This study was undertaken to evaluate the effects of noncytotoxic...
Search relevance: 71.88 | Views last month: 1 -
The present study investigated whether inhibition of deiodinase, the enzyme which converts thyroxine (T4) to the more biologically-active form, 3,5,3'-triiodothyronine (T3), would impact inflation...
Search relevance: 68.14 | Views last month: 0 -
Background Single-nucleotide polymorphisms (SNPs) are considered to be useful polymorphic markers for genetic studies of polygenic traits. Single-stranded conformational polymorphism...
Search relevance: 66.97 | Views last month: 0 -
Chemical patent from PubChem database. Patent Number: AT-E400619-T1. Title: Sustained Release Formulation. Filing Date: 1995-12-12. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: A...
Search relevance: 64.86 | Views last month: 0 -
Background: The Old-World sand fly, Phlebotomus papatasi (Scopoli), a vector of zoonotic cutaneous leishmaniasis, is usually controlled by insecticides, including anticholinesterases. Previous...
Search relevance: 62.73 | Views last month: 1 -
Aromatase inhibition is one of the chemical modes of action of concern to EPA's Endocrine Disruptor Screening Program (EDSP). In vitro bioassays that can detect aromatase inhibition are part of...
Search relevance: 59.67 | Views last month: 1 -
Chemical patent from PubChem database. Patent Number: AT-E285412-T1. Title: Novel Chemical Entity. Filing Date: 2012-10-22. Inventors: Yamamoto, Hiroshi, Schmidt, Hans. Abstract: The invention...
Search relevance: 58.45 | Views last month: 0 -
This dataset describes the results of a set of experiments, the goal of which was to evaluate the effects of protease inhibitors on the trout liver S9 substrate depletion assay. The presented...
Search relevance: 57.19 | Views last month: 0 -
The present invention provides methods for identifying peptides in a mammalian. Tsg101 protein that binds to the PTAPP (SEQ ID NO: 3) motif or L domain of human immunodeficiency virus type I...
Search relevance: 56.10 | Views last month: 0
