Found 9 datasets matching "joint-destruction".
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A possible cause of joint destruction in septic arthritis
Search relevance: 236.41 | Views last month: 0 -
Gene therapy in rheumatoid arthritis: how to target joint destruction?
Search relevance: 227.39 | Views last month: 1 -
The origin and role of IL-17, a T-cell derived cytokine, in cartilage and bone destruction during rheumatoid arthritis (RA) remain to be clarified. In human ex vivo models, addition of IL-17...
Search relevance: 65.67 | Views last month: 0 -
Destruction of cartilage and bone are hallmarks of human rheumatoid arthritis (RA), and controlling these erosive processes is the most challenging objective in the treatment of RA....
Search relevance: 59.23 | Views last month: 1 -
There is mounting evidence indicating that the synovial fibroblast is a direct effector of tissue injury and matrix remodeling in inflammatory synovitis. Through the elaboration of effector...
Search relevance: 52.06 | Views last month: 0 -
Staphylococcus aureus is one of the most important pathogens in septic arthritis. To analyse the arthritogenic properties of staphylococcal peptidoglycan (PGN), highly purified PGN from S. aureus...
Search relevance: 49.02 | Views last month: 0 -
Although early antibiotic treatment of patients with septic arthritis eradicates bacteria, joint destruction commonly results from the unregulated host inflammatory responses to infection. The...
Search relevance: 42.41 | Views last month: 0 -
There is mounting evidence for a role of the growth factor granulocyte-macrophage colony-stimulating factor (GM-CSF) in inflammatory disease, including arthritis. In the present study, we examined...
Search relevance: 35.72 | Views last month: 0 -
The influence of HLA DRB1 alleles on B-cell homeostasis was analyzed in 164 patients with rheumatoid arthritis (RA). The percentages of CD19+ B lymphocytes determined in the peripheral circulation...
Search relevance: 35.56 | Views last month: 0
