Found 17 datasets matching "lung-growth".
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Growth factors mediate tissue interactions and regulate a variety of cellular functions that are critical for normal lung development and homeostasis. Besides their involvement in lung pattern...
Search relevance: 208.91 | Views last month: 0 -
In a number of species, partial pneumonectomy initiates hormonally regulated compensatory growth of the remaining lung lobes that restores normal mass, structure and function. Compensation is...
Search relevance: 173.11 | Views last month: 0 -
Treatment of idiopathic pulmonary fibrosis patients has evolved very slowly; the fundamental approach of corticosteroids alone or in combination with other immunosuppressive agents has had little...
Search relevance: 86.17 | Views last month: 0 -
Background The outgrowth of new vessels – angiogenesis – in the tumour mass is considered to be a limiting factor of tumour growth. To inhibit the matrix lysis that is part of the tumour...
Search relevance: 57.47 | Views last month: 0 -
The large surface area, good vascularization, immense capacity for solute exchange and ultra-thinness of the alveolar epithelium are unique features of the lung that can facilitate systemic...
Search relevance: 53.38 | Views last month: 0 -
This paper reviews hypotheses about roles of angiogenesis in the pathogenesis of inflammatory disease in two organs, the synovial joint and the lung. Neovascularisation is a fundamental process...
Search relevance: 51.86 | Views last month: 0 -
TABRECTA (capmatinib) is an oral prescription medication from Novartis Pharmaceuticals Corporation, approved to treat adults with metastatic non-small cell lung cancer (NSCLC) that has a specific...
Search relevance: 50.27 | Views last month: 0 -
Allergic bronchial asthma (BA) is characterized by chronic airway inflammation, development of airway hyperreactivity and recurrent reversible airway obstruction. T-helper 2 cells and their...
Search relevance: 49.79 | Views last month: 1 -
Idiopathic pulmonary fibrosis (IPF) is a condition that has a poor prognosis, with a median survival of 4-5 years irrespective of treatment. Ziesche et al (N Engl J Med 1999, 341: 1264-1269)...
Search relevance: 47.73 | Views last month: 0 -
The matricellular protein thrombospondin 2 (TSP2) regulates a variety of cell–matrix interactions. A prominent feature of TSP2-null mice is increased microvascular density, particularly in...
Search relevance: 47.59 | Views last month: 0 -
Healthy individuals have few goblet cells in their airways, but in patients with hypersecretory diseases goblet-cell upregulation results in mucus hypersecretion, airway plugging, and death....
Search relevance: 46.54 | Views last month: 0 -
Background The brine shrimp lethality assay is considered a useful tool for preliminary assessment of toxicity. It has also been suggested for screening pharmacological activities in...
Search relevance: 31.35 | Views last month: 1 -
Background Free radicals generated in biological systems by cigarette smoke (CS) inhalation can cause oxidative stress in tissues, resulting in lipid peroxidation (LPO). In view of the...
Search relevance: 29.53 | Views last month: 1 -
The existence of a radiation bystander effect in which non-irradiated cells respond to signals from irradiated cells is well established. It raises concerns for the interpretation of risks from...
Search relevance: 27.86 | Views last month: 0 -
Age plays a major role in tumor incidence and is an important consideration when modeling the carcinogenesis process or estimating cancer risks. Epidemiological data show that from adolescence...
Search relevance: 25.06 | Views last month: 0 -
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in addition to...
Search relevance: 22.89 | Views last month: 0 -
Proton irradiation is touted for its improved tumor targeting due to the physical advantages of ion beams for radiotherapy. Recent studies from our laboratory have shown that in addition to...
Search relevance: 22.34 | Views last month: 0
